FAQ

TMOD4 gene

Known as: actin-capping protein, Sk-Tmod, skeletal tropomodulin 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1999-2015
012319992015

Related topics

Related topics

1 relation
Actin Capping Proteins

Related mentions per year

Related mentions per year

1983-2018
19801990200020102020
TMOD4 gene
Actin Capping Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Leiomodin 3 and tropomodulin 4 have overlapping functions during skeletal myofibrillogenesis.
Precise regulation of thin filament length is essential for optimal force generation during muscle contraction. The thin filament… (More)
Is this relevant?
2014
2014
Pointed-end capping by tropomodulin modulates actomyosin crossbridge formation in skeletal muscle fibers.
In skeletal muscle, thick and thin filaments are arranged in a myofibrillar lattice. Tropomodulin 1 (Tmod1) is a pointed-end… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2014
2014
Calpain-mediated proteolysis of tropomodulin isoforms leads to thin filament elongation in dystrophic skeletal muscle
Duchenne muscular dystrophy (DMD) induces sarcolemmal mechanical instability and rupture, hyperactivity of intracellular calpains… (More)
Is this relevant?
2013
2013
Alteration of tropomyosin-binding properties of tropomodulin-1 affects its capping ability and localization in skeletal myocytes.
Tropomodulin (Tmod) is an actin-capping protein that binds to the two tropomyosins (TM) at the pointed end of the actin filament… (More)
Is this relevant?
2013
2013
The switch role of the Tmod4 in the regulation of balanced development between myogenesis and adipogenesis.
Tmod4 (Tropomodulin 4) is a member of Tmod family that plays important role in thin filament length regulation and myofibril… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2011
2011
Cytoplasmic γ-actin and tropomodulin isoforms link to the sarcoplasmic reticulum in skeletal muscle fibers
The sarcoplasmic reticulum (SR) serves as the Ca(2+) reservoir for muscle contraction. Tropomodulins (Tmods) cap filamentous… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2003
2003
Tropomodulin binds to filensin intermediate filaments.
Tropomodulin (Tmod) is an actin filament pointed end capping protein found in the membrane skeleton of lens fiber cells. We… (More)
Is this relevant?
2001
2001
Genomic organization of Tropomodulins 2 and 4 and unusual intergenic and intraexonic splicing of YL-1 and Tropomodulin 4
The tropomodulins (TMODs) are a family of proteins that cap the pointed ends of actin filaments. Four TMODs have been identified… (More)
  • figure 1
  • table 1
  • table 2
  • figure 2
  • figure 3
Is this relevant?
2000
2000
Sequencing, expression analysis, and mapping of three unique human tropomodulin genes and their mouse orthologs.
Tropomodulin (TMOD) is the actin-capping protein for the slow-growing end of filamentous actin, and a neuronal-specific isoform… (More)
Is this relevant?
1999
1999
Identification of a novel tropomodulin isoform, skeletal tropomodulin, that caps actin filament pointed ends in fast skeletal muscle.
Tropomodulin (E-Tmod) is an actin filament pointed end capping protein that maintains the length of the sarcomeric actin… (More)
Is this relevant?