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TMC1 gene

Known as: transmembrane channel like 1, TRANSMEMBRANE COCHLEAR-EXPRESSED GENE 1, TMC1 
 

Topic mentions per year

Topic mentions per year

2003-2017
02420032017

Related topics

Related topics

3 relations
TMC2 geneTMC3 geneTMC4 gene

Related mentions per year

Related mentions per year

2003-2018
20002005201020152020
TMC1 gene
TMC2 gene
TMC3 gene
TMC4 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Tmc1 Point Mutation Affects Ca2+ Sensitivity and Block by Dihydrostreptomycin of the Mechanoelectrical Transducer Current of Mouse Outer Hair Cells.
UNLABELLED The transduction of sound into electrical signals depends on mechanically sensitive ion channels in the stereociliary… (More)
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2015
2015
A novel mutation in the TMC1 gene causes non-syndromic hearing loss in a Moroccan family.
Autosomal recessive non-syndromic hearing loss (ARNSHL) is one of the most common genetic diseases in human and is subject to… (More)
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2015
2015
Subunit determination of the conductance of hair-cell mechanotransducer channels.
Cochlear hair cells convert sound stimuli into electrical signals by gating of mechanically sensitive ion channels in their… (More)
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2014
2014
Tip-link protein protocadherin 15 interacts with transmembrane channel-like proteins TMC1 and TMC2.
The tip link protein protocadherin 15 (PCDH15) is a central component of the mechanotransduction complex in auditory and… (More)
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2014
2014
Mutations of TMC1 cause deafness by disrupting mechanoelectrical transduction.
OBJECTIVE Mutations of transmembrane channel-like 1 gene (TMC1) can cause dominant (DFNA36) or recessive (DFNB7/B11) deafness. In… (More)
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Highly Cited
2011
Highly Cited
2011
Targeted genomic capture and massively parallel sequencing to identify genes for hereditary hearing loss in middle eastern families
Identification of genes responsible for medically important traits is a major challenge in human genetics. Due to the genetic… (More)
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2009
2009
Amino acid 572 in TMC1: hot spot or critical functional residue for dominant mutations causing hearing impairment
Two different missense mutations, p.D572N and p.D572H, affecting the same nucleotide and codon of the TMC1 gene were earlier… (More)
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2008
2008
TMC1 but not TMC2 is responsible for autosomal recessive nonsyndromic hearing impairment in Tunisian families.
Hereditary nonsyndromic hearing impairment (HI) is extremely heterogeneous. Mutations of the transmembrane channel-like gene 1… (More)
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2007
2007
A novel mutation at the DFNA36 hearing loss locus reveals a critical function and potential genotype-phenotype correlation for amino acid-572 of TMC1.
We ascertained a North American Caucasian family (LMG248) segregating autosomal dominant, non-syndromic, post-lingual… (More)
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2005
2005
Novel sequence variants in the TMC1 gene in Pakistani families with autosomal recessive hearing impairment.
Though many hearing impairment genes have been identified, only a few of these genes have been screened in population studies… (More)
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