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TMBIM1 gene

Known as: LFG3, PP1201, transmembrane BAX inhibitor motif containing 1 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Innate immune regulatory networks in hepatic lipid metabolism
Hepatic lipid metabolism is closely associated with certain diseases, such as obesity, diabetes, fatty liver, and hepatic… 
2018
2018
Up regulated Tmbim1 activation promotes high fat diet (HFD)-induced cardiomyopathy by enhancement of inflammation and oxidative stress.
Highly Cited
2017
Highly Cited
2017
Tmbim1 is a multivesicular body regulator that protects against non-alcoholic fatty liver disease in mice and monkeys by targeting the lysosomal degradation of Tlr4
Non-alcoholic steatohepatitis (NASH) is an increasingly prevalent liver pathology that can progress from non-alcoholic fatty… 
2017
2017
Targeting Transmembrane BAX Inhibitor Motif Containing 1 Alleviates Pathological Cardiac Hypertrophy
Background: Cardiac hypertrophy and its resultant heart failure are among the most common causes of mortality worldwide. Abnormal… 
2016
2016
Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease
To identify new risk loci for colorectal cancer (CRC), we conducted a meta-analysis of seven genome-wide association studies… 
Highly Cited
2015
Highly Cited
2015
The transmembrane Bax inhibitor motif (TMBIM) containing protein family: Tissue expression, intracellular localization and effects on the ER CA²⁺-filling state.
2011
2011
A shear stress responsive gene product PP1201 protects against Fas-mediated apoptosis by reducing Fas expression on the cell surface
Cells that form vascular system employ different mechanisms to offset deleterious consequences of exposure to cytokines and cells… 
2006
2006
RECS1 deficiency in mice induces susceptibility to cystic medial degeneration.
RECS1 is a novel shear stress-responsive gene that encodes a protein putatively forming seven-span transmembrane domains. We… 
2006
2006
RECS1 is a negative regulator of matrix metalloproteinase-9 production and aged RECS1 knockout mice are prone to aortic dilation.
BACKGROUND RECS1 is a mechanical stress responsive gene and RECS1 knockout (KO) mice (older than 14 months) are prone to cystic… 
Highly Cited
1983
Highly Cited
1983
The neural basis of footshock analgesia: The role of specific ventral medullary nuclei
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