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TM6SF2 gene

Known as: Lpr4, KIAA1926, transmembrane 6 superfamily member 2 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Genes
HAPLN4 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
[Construction of transmembrane 6 superfamily member 2 E167K gene knock-in mouse model by using CRISPR/Cas9 technology].
Objective: To construct a transmembrane 6 superfamily member 2 (Tm6sf2) E167K gene knock-in mouse model. Methods: The plasmid was… 
2019
2019
TM6SF2 E167K Variant Overexpression Promotes Expression of Inflammatory Cytokines in the HCC Cell Line HEPA 1-6
Abstract Background and Aims: Accumulated evidence has shown that chronic liver inflammation is one of the main risks of… 
Review
2019
Review
2019
[Research progress of single-nucleotide polymorphism in theTM6SF2 rs58542926].
Transmembrane 6 superfamily member 2 (TM6SF2) is a recently discovered gene, which is located on the chromosome 19 (19p12) and… 
2018
2018
PNPLA3 p.I148M and TM6SF2 p.E167K variants do not predispose to liver injury in cholestatic liver diseases: A prospective analysis of 178 patients with PSC
Background The adiponutrin (PNPLA3) p.I148M and transmembrane 6 superfamily member 2 (TM6SF2) p.E167K variants represent major… 
2018
2018
[Effects of PNPLA3, TM6SF2 gene polymorphisms and its interactions with smoking and alcohol drinking on hepatitis B virus-associated hepatocellular carcinoma].
Objective: To explore the SNP effects of patatin-like phospholipase domain which containing 3 (PNPLA3), transmembrane 6… 
2017
2017
The additive effects of the TM6SF2 E167K and PNPLA3 I148M polymorphisms on lipid metabolism
There is a genetic susceptibility for nonalcoholic fatty liver disease (NAFLD). To examine the role of genetic factors in the… 
2017
2017
TM6SF2 rs58542926 Polymorphism is not Associated With Risk of Steatosis or Fibrosis in Chilean Patients With Chronic Hepatitis C
Background: The polymorphism rs58542926 C > T (E167K) in the gene of transmembrane 6 superfamily member 2 (TM6SF2) has been… 
2016
2016
Reduction of Caloric Intake Might Override the Prosteatotic Effects of the PNPLA3 p.I148M and TM6SF2 p.E167K Variants in Patients with Fatty Liver: Ultrasound-Based Prospective Study
Background: The adiponutrin (PNPLA3) p.I148M and transmembrane 6 superfamily member 2 (TM6SF2) p.E167K variants represent risk… 
Highly Cited
2015
Highly Cited
2015
Transmembrane 6 superfamily member 2 gene E167K variant impacts on steatosis and liver damage in chronic hepatitis C patients
Steatosis and inherited host factors influence liver damage progression in chronic hepatitis C (CHC). The transmembrane 6… 
2014
2014
Genetic and metabolic studies of APOE , PCSK 9 TM 6 SF 2 and PNPLA 3
Lipids including fatty acids (FAs), triglycerides (TGs), cholesterol and cholesterol esters (CEs) are hydrophobic molecules… 
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