TLR4 Agonist GLA-SE

Known as: GLA-SE, Glucopyranosyl Lipid Adjuvant-Stable Emulsion, Glucopyranosyl Lipid A in Stable Emulsion 
A synthetic lipid A derivative and toll-like receptor 4 (TLR4) agonist, in an oil-in-water emulsion, with potential immunoadjuvant activity. Upon… (More)

Topic mentions per year

Topic mentions per year

2010-2016
05101520102016

Papers overview

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2016
2016
The Toll-like receptor 4 agonist glucopyranosyl lipid adjuvant formulated in a stable emulsion (GLA-SE) promotes strong TH1 and… (More)
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2015
2015
Key antigens of Leishmania species identified in the context of host responses in Leishmania-exposed individuals from disease… (More)
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2013
2013
BACKGROUND Recent advances in rational adjuvant design and antigen selection have enabled a new generation of vaccines with… (More)
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2012
2012
The natural TLR4 agonist lipopolysaccharide (LPS) has notable adjuvant activity. However, it is not useful as a vaccine adjuvant… (More)
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2012
2012
BACKGROUND The decline in influenza vaccine efficacy in older adults is associated with a limited ability of current split-virus… (More)
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2012
2012
An effective protein-based vaccine for tuberculosis will require a safe and effective adjuvant. There are few adjuvants in… (More)
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2012
2012
BACKGROUND Toll-like receptor (TLR)4 agonists are known potent immunostimulatory compounds. These compounds can be formulated as… (More)
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2012
2012
Staphylococcus aureus (S. aureus) is a human pathogen associated with skin and soft tissue infections (SSTI) and life threatening… (More)
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2011
2011
Tuberculosis is a major health concern. Non-living tuberculosis (TB) vaccine candidates may not only be safer than the current… (More)
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2011
2011
In this study, we assessed the immune response of two Leishmania donovani recombinant proteins: iron superoxide dismutase B1… (More)
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