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THOP1 gene

Known as: THIMET OLIGOPEPTIDASE 1, THOP1, TOP 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Purpose Current evidence suggests that retinal neurodegeneration is an early event in the pathogenesis of diabetic retinopathy… Expand
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2013
2013
Significance Import of proteins to mitochondria and chloroplasts is essential for organelle biogenesis and organism survival… Expand
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Highly Cited
2009
Highly Cited
2009
Thimet oligopeptidase (EC 3.4.24.15; EP24.15) is an intracellular enzyme that has been proposed to metabolize peptides within… Expand
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2007
2007
  • R. Jain, M. Chan
  • Biochemical and biophysical research…
  • 2007
  • Corpus ID: 7861094
Protein degradation is an essential quality control and regulatory function in organisms ranging from bacteria to eukaryotes. In… Expand
2003
2003
Thimet oligopeptidase is a metalloenzyme involved in regulating neuropeptide processing. Three cysteine residues (246, 248, 253… Expand
1999
1999
Immunohistochemistry was used to analyze the rat brain distribution of thimet oligopeptidase and neurolysin. Both enzymes appear… Expand
Highly Cited
1999
Highly Cited
1999
In this study we investigated the fate of a class of proteasome-generated oligopeptides, exposing them to the crude cytosol of… Expand
1995
1995
The substrate-size specificity of human thimet oligopeptidase (EC 3.4.24.15) was investigated with oligomers of glycyl-prolyl… Expand
1994
1994
We have previously determined the amino acid sequence of porcine soluble angiotensin-binding protein (sABP) by cDNA cloning and… Expand
Highly Cited
1993
Highly Cited
1993
We have purified human thimet oligopeptidase to homogeneity from erythrocytes, and compared it with the enzyme from rat testis… Expand
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