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TGFB1 gene

Known as: CED, TGFB1, transforming growth factor beta 1 
This gene plays a role in cell growth, proliferation and biogenesis/organization. It is also involved in the inhibition of apoptosis.
National Institutes of Health

Related topics

Related topics

13 relations
Camurati-Engelmann SyndromeCell Differentiation processCell ProliferationCell Proliferation Regulatory Process

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Possible relationship between fibrosis of IgG4-related thymitis and the profibrotic cytokines, transforming growth factor beta 1, interleukin 1 beta and interferon gamma: a case report
BackgroundIgG4-related disease often forms a mass and the affected lesion is clinically removed because the mass cannot be… 
2016
2016
Clinical diagnosis and mutation analysis of a Chinese family with Camurati-Engelmann disease
Camurati-Engelmann disease (CED) is a rare autosomal dominant bone disorder caused by a mutation in transforming growth factor β1… 
2012
2012
Susceptibility to ankylosing spondylitis: evidence for the role of ERAP1, TGFb1 and TLR9 gene polymorphisms
Genetic factors are thought to be crucial in the pathogenesis of ankylosing spondylitis (AS). Recent studies have reported that… 
2011
2011
Family Analysis of Linkage and Association of HLA-DRB1, CTLA4, TGFB1, IL4, CCR5, RANTES, MMP9 and TIMP1 Gene Polymorphisms with Multiple Sclerosis
Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease of the central nervous system (CNS). Proteins of the immune… 
2008
2008
[Polymorphism of codon25 in signal peptide region of transforming growth factor beta 1 and its association with chronic hepatitis C virus infection].
OBJECTIVE To investigate the possible relationship between polymorphism of codon25 in signal peptide region of transforming… 
2004
2004
Gender-related association between the TGFB1+869 polymorphism and multiple sclerosis.
Our objective was to investigate whether polymorphisms and haplotypes in the TGFB1 gene are associated with susceptibility or… 
2003
2003
Growth inhibitory signalling by TGFbeta is blocked in Ras-transformed intestinal epithelial cells at a post-receptor locus.
2000
2000
Loss of transforming growth factor-beta (TGF-beta) receptor type I mediates TGF-beta resistance in human papillomavirus type 16-transformed human keratinocytes at late stages of in vitro progression.
Human keratinocytes (HKc) immortalized by human papillomavirus type 16 DNA (HKc/HPV16) progress toward malignancy through growth… 
1999
1999
Truncation of the TGF-beta type II receptor gene results in insensitivity to TGF-beta in human gastric cancer cells.
The transforming growth factor-beta (TGF-beta receptor system has been implicated in the development of resistance to the growth… 
1999
1999
Use of representational difference analysis to study the effect of TGFB on the expression profile of a pancreatic cancer cell line
It has been shown that TGFBs, their receptors, or downstream targets show genetic alterations in pancreatic cancer. This study… 
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