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TFR2 gene
Known as:
TFRC2
, Transferrin Receptor 2 Gene
, TRANSFERRIN RECEPTOR 2
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This gene plays a role in iron metabolism.
National Institutes of Health
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Related topics
Related topics
10 relations
Erythropoiesis
HEMOCHROMATOSIS, TYPE 3
Homo sapiens
Ionophore activity
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TFR2 wt Allele
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Reduced hepcidin level features osteoporosis
B. Liu
,
Cai-Li Liu
,
Weifeng Zhong
,
Min Song
,
S. Du
,
Jianli Su
Experimental and Therapeutic Medicine
2018
Corpus ID: 52158369
Osteoporosis (OP) is a common serious skeletal disorder marked by increased risk of bone fracture due to fragility. OP has been…
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2017
2017
Effects of IL-10 on iron metabolism in LPS-induced inflammatory mice via modulating hepcidin expression.
P. Huang
,
Jun Wang
,
X. Lin
,
Yang Ff
,
Tan Jh
European Review for Medical and Pharmacological…
2017
Corpus ID: 4933492
OBJECTIVE Body's iron metabolism is at one dynamic balance status, and abnormal iron metabolism may lead to renal anemia…
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2016
2016
Bone Morphogenetic Protein-6 Mutations Take Their Place in Iron Overload Diseases.
M. Kleven
,
C. Enns
,
An-Sheng Zhang
Gastroenterology
2016
Corpus ID: 7643844
2015
2015
CD81 Promotes Both the Degradation of Transferrin Receptor 2 (TfR2) and the Tfr2-mediated Maintenance of Hepcidin Expression*
Juxing Chen
,
C. Enns
Journal of Biological Chemistry
2015
Corpus ID: 33529641
Background: Loss of function mutations in TfR2 cause iron overload in the body. Results: CD81, a scaffold protein, controls the…
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2015
2015
Hepatocyte Nuclear Factor 4 (cid:2) Controls Iron Metabolism and Regulates Transferrin Receptor 2 in Mouse Liver *
Shunsuke Matsuo
,
Masayuki Ogawa
,
+9 authors
Yusuke Inoue
2015
Corpus ID: 23212052
Iron is an essential element in biological systems, but excess iron promotes the formation of reactive oxygen species, resulting…
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Review
2011
Review
2011
The molecular pathogenesis of hereditary hemochromatosis.
Jodie L Babitt
,
Herbert Y. Lin
Seminars in liver disease (Print)
2011
Corpus ID: 5741590
Hereditary hemochromatosis is a genetic disorder of iron overload. Over the past 15 years, significant advances have been made in…
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2008
2008
HFE association with transferrin receptor 2 increases cellular uptake of transferrin-bound iron.
A. Waheed
,
R. Britton
,
J. Grubb
,
W. Sly
,
R. Fleming
Archives of Biochemistry and Biophysics
2008
Corpus ID: 20629671
Review
2005
Review
2005
Advances in understanding the molecular basis for the regulation of dietary iron absorption
R. Fleming
Current Opinion in Gastroenterology
2005
Corpus ID: 22817973
Purpose of review The number of newly identified genes participating in the regulation of iron homeostasis has continued to…
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2003
2003
Human platelets express hemochromatosis protein (HFE) and transferrin receptor 2
Jokke Hannuksela
,
S. Parkkila
,
+4 authors
W. Sly
European Journal of Haematology
2003
Corpus ID: 20875125
Abstract: Objectives: While body iron status may influence platelets, little information is available about platelet expression…
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2003
2003
Heterotypic interactions between transferrin receptor and transferrin receptor 2.
T. Vogt
,
Aaron D. Blackwell
,
A. M. Giannetti
,
P. Bjorkman
,
C. Enns
Blood
2003
Corpus ID: 11967235
Cellular iron uptake in most tissues occurs via endocytosis of diferric transferrin (Tf) bound to the transferrin receptor (TfR…
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