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TFF3 gene

Known as: ITF, Trefoil Factor 3 (Intestinal) Gene, HITF 
This gene is involved in maintenance of the intestinal mucosa.
National Institutes of Health

Related topics

Related topics

5 relations
DigestionTFF3 protein, humanTrefoil Factor-3cell motility

Papers overview

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Highly Cited
2015
Highly Cited
2015
Monocyte mediated brain targeting delivery of macromolecular drug for the therapy of depression.
2012
2012
Consumers' beliefs on indigenous and traditional foods and acceptance of products made with cow pea leaves
The study was conducted to obtain background information on consumers’ beliefs on Indigenous and Traditional Foods (ITF) and to… 
2010
2010
Trefoil factor 3 is induced during degenerative and inflammatory joint disease, activates matrix metalloproteinases, and enhances apoptosis of articular cartilage chondrocytes.
OBJECTIVE Trefoil factor 3 (TFF3, also known as intestinal trefoil factor) is a member of a family of protease-resistant peptides… 
Highly Cited
2008
Highly Cited
2008
Intestinal Trefoil Factor/TFF3 Promotes Re-epithelialization of Corneal Wounds*
Disorders of wound healing characterized by impaired or delayed re-epithelialization are a serious medical problem. These… 
2006
2006
Systemically administered trefoil factors are secreted into the gastric lumen and increase the viscosity of gastric contents
Trefoil factors (TFFs) secreted by mucus‐producing cells are essential for the defence of the gastrointestinal mucosa. TFFs… 
Highly Cited
2003
Highly Cited
2003
Selective abrogation of the proinvasive activity of the trefoil peptides pS2 and spasmolytic polypeptide by disruption of the EGF receptor signaling pathways in kidney and colonic cancer cells
Trefoil peptides (TFFs) are now considered as scatter factors, proinvasive and angiogenic agents acting through cyclooxygenase-2… 
2001
2001
Trefoil peptides promote restitution of wounded corneal epithelial cells.
The ocular surface shares many characteristics with mucosal surfaces. In both, healing is regulated by peptide growth factors… 
1999
1999
Goblet-cell-specific transcription of mouse intestinal trefoil factor gene results from collaboration of complex series of positive and negative regulatory elements.
Intestinal trefoil factor (ITF) is expressed selectively in intestinal goblet cells. Previous studies of the rat ITF gene… 
Highly Cited
1998
Highly Cited
1998
Intestinal trefoil factor induces inactivation of extracellular signal-regulated protein kinase in intestinal epithelial cells.
Intestinal trefoil factor (ITF), a small, compact protease-resistant peptide, is abundantly expressed in goblet cells of large… 
Highly Cited
1998
Highly Cited
1998
Short-chain fatty acids inhibit intestinal trefoil factor gene expression in colon cancer cells.
Intestinal trefoil factor (ITF) gene expression was detected in five colon cancer cell lines. ITF was synthesized by mucous cells… 
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