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TFAP2C gene

Known as: hAP-2g, ESTROGEN RECEPTOR FACTOR 1, TFAP2C 
This gene plays a role in transcriptional regulation of genes which are required for development of ectodermal tissues.
National Institutes of Health

Related topics

Related topics

7 relations
Cell Differentiation processHomo sapiensTranscription Factor AP-2 GammaTranscriptional Regulation

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TFAP2C wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2019
Highly Cited
2019
TFAP2C- and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage Commitment.
Highly Cited
2018
Highly Cited
2018
The TFAP2C-Regulated OCT4 Naive Enhancer Is Involved in Human Germline Formation
Highly Cited
2017
Highly Cited
2017
TFAP2C promotes lung tumorigenesis and aggressiveness through miR-183- and miR-33a-mediated cell cycle regulation
Non-small cell lung cancer (NSCLC) remains one of the leading causes of death worldwide, and thus new molecular targets need to… 
Highly Cited
2016
Highly Cited
2016
TFAP2C-mediated upregulation of TGFBR1 promotes lung tumorigenesis and epithelial–mesenchymal transition
TFAP2C (transcription factor-activating enhancer-binding protein 2C) expression has been positively correlated with poor… 
2013
2013
Expression of the RET Proto-oncogene Is Regulated by TFAP2C in Breast Cancer Independent of the Estrogen Receptor
BackgroundThe RET proto-oncogene is expressed as part of the estrogen receptor (ER) cluster in breast cancer. We sought to… 
Highly Cited
2012
Highly Cited
2012
Histone Demethylase KDM5B Collaborates with TFAP2C and Myc To Repress the Cell Cycle Inhibitor p21cip (CDKN1A)
ABSTRACT The TFAP2C transcription factor has been shown to downregulate transcription of the universal cell cycle inhibitor… 
Review
2012
Review
2012
The role of transcription factor Tcfap2c/TFAP2C in trophectoderm development.
Highly Cited
2011
Highly Cited
2011
CpG island methylation profiling in human salivary gland adenoid cystic carcinoma
DNA methylation is a fundamental epigenetic event associated with physiologic and pathologic conditions, including cancer… 
Highly Cited
2010
Highly Cited
2010
Identification of primary gene targets of TFAP2C in hormone responsive breast carcinoma cells
The TFAP2C transcription factor is involved in mammary development, differentiation, and oncogenesis. Previous studies… 
Highly Cited
1995
Highly Cited
1995
Transcriptional regulation of estrogen receptor in breast carcinomas
An important transcriptional regulatory element of the estrogen receptor (ER) gene that binds a protein expressed in ER-positive… 
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