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TERT Deficiency
A condition of decreased or absent presence of telomerase reverse transcriptase. Deficiency of this protein is associated with autosomal dominant…
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National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Telomerase reverse transcriptase ameliorates lung fibrosis by protecting alveolar epithelial cells against senescence
Tianju Liu
,
F. Gonzalez De los Santos
,
+4 authors
S. Phan
Journal of Biological Chemistry
2019
Corpus ID: 122574428
Mutations in the genes encoding telomerase reverse transcriptase (TERT) and telomerase's RNA components as well as shortened…
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2019
2019
Telomerase Deficiency Predisposes to Heart Failure and Ischemia-Reperfusion Injury
K. Ait-Aissa
,
J. Heisner
,
+6 authors
Andreas M Beyer
Frontiers in Cardiovascular Medicine
2019
Corpus ID: 89617238
Coronary heart disease remains one of the main cause of death worldwide. With lack of successful treatment, new therapeutic…
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2017
2017
Telomerase Reverse Transcriptase Deficiency Prevents Neointima Formation Through Chromatin Silencing of E2F1 Target Genes
Elizabeth B Endorf
,
Hua Qing
,
+6 authors
D. Bruemmer
Arteriosclerosis, Thrombosis and Vascular Biology
2017
Corpus ID: 9307148
Objective— Aberrant proliferation of smooth muscle cells (SMC) in response to injury induces pathological vascular remodeling…
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2016
2016
Reactivation of Tert in the medial prefrontal cortex and hippocampus rescues aggression and depression of Tert−/− mice
Qi-Gang Zhou
,
Hy Wu
,
+7 authors
H. Suh
Translational Psychiatry
2016
Corpus ID: 25946551
The role of telomerase reverse transcriptase (TERT) has been extensively investigated in the contexts of aging and cancer…
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2015
2015
Conditional Knockout of Telomerase Reverse Transcriptase in Mesenchymal Cells Impairs Mouse Pulmonary Fibrosis
Tianju Liu
,
Hongfeng Yu
,
+8 authors
Yong Zhou
PLoS ONE
2015
Corpus ID: 18427845
Telomerase is typically expressed in cellular populations capable of extended replication, such as germ cells, tumor cells, and…
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Highly Cited
2011
Highly Cited
2011
Telomerase Activation in Atherosclerosis and Induction of Telomerase Reverse Transcriptase Expression by Inflammatory Stimuli in Macrophages
F. Gizard
,
E. B. Heywood
,
+6 authors
D. Bruemmer
Arteriosclerosis, Thrombosis and Vascular Biology
2011
Corpus ID: 30279201
Objective—Telomerase serves as a critical regulator of tissue renewal. Although telomerase activity is inducible in response to…
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2011
2011
Telomerase Deficiency in Bone Marrow–Derived Cells Attenuates Angiotensin II–Induced Abdominal Aortic Aneurysm Formation
H. Findeisen
,
F. Gizard
,
+7 authors
D. Bruemmer
Arteriosclerosis, Thrombosis and Vascular Biology
2011
Corpus ID: 26944127
Objective—Abdominal aortic aneurysms (AAA) are an age-related vascular disease and an important cause of morbidity and mortality…
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2010
2010
Deficiency of telomerase activity aggravates the blood–brain barrier disruption and neuroinflammatory responses in a model of experimental stroke
Bei Zhang
,
Lei Chen
,
+7 authors
M. Toborek
Journal of Neuroscience Research
2010
Corpus ID: 11769331
Epidemiology and genetic studies indicate that patients with telomere length shorter than average are at higher risk of dying…
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