TERT Deficiency

A condition of decreased or absent presence of telomerase reverse transcriptase. Deficiency of this protein is associated with autosomal dominant… (More)
National Institutes of Health

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2017
2017
OBJECTIVE Aberrant proliferation of smooth muscle cells (SMC) in response to injury induces pathological vascular remodeling… (More)
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2016
2016
The role of telomerase reverse transcriptase (TERT) has been extensively investigated in the contexts of aging and cancer… (More)
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2015
2015
Telomerase is typically expressed in cellular populations capable of extended replication, such as germ cells, tumor cells, and… (More)
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2011
2011
OBJECTIVE Telomerase serves as a critical regulator of tissue renewal. Although telomerase activity is inducible in response to… (More)
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2011
2011
OBJECTIVE Abdominal aortic aneurysms (AAA) are an age-related vascular disease and an important cause of morbidity and mortality… (More)
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2010
2010
Epidemiology and genetic studies indicate that patients with telomere length shorter than average are at higher risk of dying… (More)
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