FAQ

TDGF1P6 gene

Known as: teratocarcinoma-derived growth factor 1 pseudogene 6, CR-6, CRIPTO-6 
 

Topic mentions per year

Topic mentions per year

1987-2015
01219872015

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Synthesis and in vitro, ex-vivo and in vivo activity of hybrid compounds linking a potent ROS and RNS scavenger activity with diverse substrates addressed to pass across the blood-brain barrier.
The synthesis of a small library of CR-6 (a potent ROS and RNS scavenger agent) derivatives bearing covalent linkage with… (More)
Is this relevant?
2010
2010
Antioxidant CR-6 protects against reperfusion injury after a transient episode of focal brain ischemia in rats.
Oxidative and nitrosative stress are targets for intervention after ischemia/reperfusion. The aim of this study was to explore… (More)
Is this relevant?
2009
2009
Participation of oxidative stress on rat middle cerebral artery changes induced by focal cerebral ischemia: beneficial effects of 3,4-dihydro-6-hydroxy-7-methoxy-2,2-dimethyl-1(2H)-benzopyran (CR-6).
Cerebral ischemia followed by reperfusion alters vessel properties of brain arteries in rats, inducing an inflammatory response… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2008
2008
Inheritance of high oleic acid content in safflower
Safflower (Carthamus tinctorius L.) oil with high oleic acid content (>75%) has a great value for both food and non-food uses… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2007
2007
CR-6 protects glutathione peroxidase activity in experimental diabetes.
Antioxidants can be useful as a supportive therapy in diabetes, and we try to elucidate some of the mechanisms by which these… (More)
Is this relevant?
2007
2007
Oxidative Stress in Rat Retina and Hippocampus after Chronic MDMA (‘ecstasy’) Administration
The effects of MDMA administration on oxidative stress markers in rat eye and hippocampus, and the neuroprotective effects of the… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2006
2006
The radical scavenger CR-6 protects SH-SY5Y neuroblastoma cells from oxidative stress-induced apoptosis: effect on survival pathways.
Reactive oxygen species (ROS) and oxidative stress have long been linked to cell death of neurons in many neurodegenerative… (More)
Is this relevant?
2004
2004
Oxidative stress-induced apoptosis in retinal photoreceptor cells is mediated by calpains and caspases and blocked by the oxygen radical scavenger CR-6.
A critical role for reactive oxygen species (ROS) in photoreceptor apoptosis has been established. However, the exact molecular… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2001
2001
Role of nitric oxide and cyclic GMP in glutamate-induced neuronal death
Glutamate is the main excitatory neurotransmitter in mammals. However, excessive activation of glutamate receptors is neurotoxic… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 6
Is this relevant?
1999
1999
Prevention of glutamate neurotoxicity in cultured neurons by 3,4-dihydro-6-hydroxy-7-methoxy-2,2-dimethyl-1(2H)-benzopyran (CR-6), a scavenger of nitric oxide.
Glutamate neurotoxicity in cerebellar neurons in culture is mediated by excessive production of nitric oxide (NO). We anticipated… (More)
Is this relevant?