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TAZ, IVS1DS, G-C, +5

National Institutes of Health

Papers overview

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2019
2019
Insulin resistance is a major factor in obesity-linked type 2 diabetes. PPARγ is a master regulator of adipogenesis, and small… Expand
2019
2019
The Hippo pathway has emerged as a key signaling pathway that regulates a broad range of biological functions, and dysregulation… Expand
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Review
2018
Review
2018
ABSTRACT Introduction: The Hippo pathway represents a new and intriguing opportunity for the treatment of cancer. Activation or… Expand
2018
2018
Our previously published study demonstrated that mammalian target of rapamycin complex 2 (mTORC2) signaling mediates TGFβ1… Expand
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Highly Cited
2015
Highly Cited
2015
YAP (yes-associated protein) and TAZ are oncogenic transcriptional co-activators downstream of the Hippo tumor-suppressor pathway… Expand
Highly Cited
2015
Highly Cited
2015
The Hippo pathway plays a crucial role in growth control, proliferation and tumor suppression. Activity of the signaling pathway… Expand
Highly Cited
2015
Highly Cited
2015
The molecular origins of fibrosis affecting multiple tissue beds remain incompletely defined. Previously, we delineated the… Expand
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Highly Cited
2012
Highly Cited
2012
The structure of the complex between the transcription cofactor Vgll1 and the transcription factor TEAD4, the mammalian… Expand
Highly Cited
2011
Highly Cited
2011
Barth's syndrome (BTHS) is an X-linked mitochondrial disease that is due to a mutation in the Tafazzin (TAZ) gene. Based on… Expand
Highly Cited
2010
Highly Cited
2010
The Hippo pathway regulates organ size by controlling both cell proliferation and apoptosis. TAZ functions as a transcriptional… Expand
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