TAZ, IVS1DS, G-C, +5
National Institutes of Health
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The Hippo pathway has emerged as a key signaling pathway that regulates a broad range of biological functions, and dysregulation…
Purpose: Synovial sarcoma is a soft tissue malignancy characterized by a reciprocal t(X;18) translocation. The chimeric SS18-SSX…
Yes Associated Protein 1 (YAP) and Transcriptional coactivator with PDZ-Binding Motif (TAZ) have gained notoriety for their…
Insulin resistance (IR) is an important mechanism of pathogenesis of endometrial cancer (EC) and explains the pathogenic…
The molecular origins of fibrosis affecting multiple tissue beds remain incompletely defined. Previously, we delineated the…
The transcriptional co-activator with PDZ-binding motif (TAZ) is a downstream effector of the Hippo tumor suppressor pathway…
Barth's syndrome (BTHS) is an X-linked mitochondrial disease that is due to a mutation in the Tafazzin (TAZ) gene. Based on…