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TAS 301

Known as: TAS-301, TAS301 
 
National Institutes of Health

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2018
2018
Ru-Catalyzed dehydrogenative synthesis of antimalarial arylidene oxindoles.
Ru(ii)-NHC catalyzes α-olefination of 2-oxindoles using diaryl methanols in the absence of an acceptor. A wide array of… Expand
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2003
2003
Highly Stabilized Amorphous 3-bis(4-Methoxyphenyl)methylene-2-indolinone (TAS-301) in Melt-Adsorbed Products with Silicate Compounds
Abstract 3-Bis(4-Methoxyphenyl)methylene-2-indolinone (TAS-301) is a poorly water-soluble drug showing low oral bioavailability… Expand
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Highly Cited
2002
Highly Cited
2002
Improvement of solubility and oral bioavailability of a poorly water-soluble drug, TAS-301, by its melt-adsorption on a porous calcium silicate.
The aim of the present study was to improve the solubility and oral bioavailability of a poorly water-soluble drug, 3-bis(4… Expand
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2001
2001
TAS-301, a New Synthetic Inhibitor of Neointimal Thickening after Balloon Injury, Inhibits Calcium-Dependent Signal Transduction and Cytoskeletal Reorganization
We previously demonstrated that a recently synthesized drug, TAS-301 [3-bis(4-methoxyphenyl)methylene-2-indolinone], inhibited… Expand
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2000
2000
Inhibitory effect of TAS-301, a new synthesized constrictive remodeling regulator, on renarrowing after balloon overstretch injury of porcine coronary artery.
The purpose of this study was to determine the efficacy and the possible mechanism of action of a recently synthesized drug, TAS… Expand
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2000
2000
TAS-301 blocks receptor-operated calcium influx and inhibits rat vascular smooth muscle cell proliferation induced by basic fibroblast growth factor and platelet-derived growth factor.
The purpose of this study was to determine the effect of a recently synthesized drug, TAS-301 [3-bis(4-methoxyphenyl)methylene-2… Expand
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1998
1998
TAS-301, an inhibitor of smooth muscle cell migration and proliferation, inhibits intimal thickening after balloon injury to rat carotid arteries.
The purpose of this study was to determine the efficacy and the possible mechanism of action of a recently synthesized drug, TAS… Expand
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1997
1997
3.P.330 New therapeutic possibility with TAS-301 for restonosis by regulating vascular remodeling: Insight from porcine coronary stenosis model
 
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1997
1997
3.P.327 Newly synthesized TAS-301, by regulating the migration process, reduces the neointimal thickening after balloon injury in rats
 
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