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TAS-117

 
National Institutes of Health

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2019
2019
Polycomb repressive complex 2 (PRC2) components, EZH2 and its homolog EZH1, and PI3K/Akt signaling pathway are focal points as… Expand
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2019
2019
Abstract Background TAS-117 is a novel highly potent and selective oral allosteric AKT inhibitor. This study investigated the… Expand
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2014
2014
The PI3K/Akt pathway plays a crucial role in the pathogenesis of multiple myeloma (MM) in the bone marrow (BM) milieu. However… Expand
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2013
2013
  • Teruhiro Utsugi
  • Japanese journal of clinical oncology
  • 2013
  • Corpus ID: 16915823
Many pharmaceutical companies worldwide specialize in oncology drug development and marketing. Among them, we have continued to… Expand
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2012
2012
Abstract 942 The PI3K/Akt pathway mediates multiple myeloma (MM) cell growth and drug resistance, and targeting this molecule is… Expand
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