TAL2 gene

Known as: T-CELL ACUTE LYMPHOCYTIC LEUKEMIA 2, T-Cell Acute Lymphocytic Leukemia 2 Gene, bHLHa19 
This gene is involved in transcriptional regulation. It plays a role in T-cell acute lymphocytic leukemia.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1991-2018
01219912018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
TAL2 is a transcription factor required in the normal development of mouse brain. In a previous study, we demonstrated that the… (More)
Is this relevant?
2012
2012
The aim of this study was to better understand the mechanisms of tumor development and disease progression in human… (More)
  • table I
  • table II
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
2010
2010
The purpose of this study was to screen cancer-related genes and to identify histopathological gene expression patterns as… (More)
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
2004
Highly Cited
2004
The activation of oncogenic transcription factors defines distinct molecular subsets of T-cell acute lymphoblastic leukaemia and… (More)
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Most lymphoid malignancies are initiated by specific chromosomal translocations between immunoglobulin (Ig)/T cell receptor (TCR… (More)
  • table I
  • table III
  • table IV
  • figure 1
  • figure 2
Is this relevant?
2000
2000
Transcription factors are commonly involved in leukemia by activation through chromosomal translocations and normally function in… (More)
Is this relevant?
1996
1996
TAL1 is a basic helix-loop-helix (bHLH) protein involved in hematopoietic development. In T cell acute lymphoblastic leukemic… (More)
Is this relevant?
Highly Cited
1994
Highly Cited
1994
The protein products of proto-oncogenes implicated in T cell acute lymphoblastic leukemia include two distinct families of… (More)
Is this relevant?
1994
1994
The TAL2 gene is activated as a result of the (7;9) (q34;q32) translocation, a chromosome defect found in the malignant cells of… (More)
Is this relevant?
1991
1991
Tumor-specific alteration of the TAL1 gene occurs in almost 25% of patients with T-cell acute lymphoblastic leukemia (T-ALL). We… (More)
Is this relevant?