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TAL2 gene

Known as: T-CELL ACUTE LYMPHOCYTIC LEUKEMIA 2, T-Cell Acute Lymphocytic Leukemia 2 Gene, bHLHa19 
This gene is involved in transcriptional regulation. It plays a role in T-cell acute lymphocytic leukemia.
National Institutes of Health

Related topics

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5 relations
Homo sapiensT Lymphoblastic Leukemia/LymphomaTAL2 protein, humanTranscriptional Regulation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
RUNX1 in T-ALL: tumor suppressive or oncogenic?
In this issue of Blood , Choi et al demonstrated an oncogenic role of RUNX1 in T-cell acute lymphoblastic leukemia (T-ALL), 1… 
2017
2017
Relapsing Pediatric T-Cell Acute Lymphoblastic Leukemia Downregulates T-Cell Properties and Upregulates Cell Adhesion
Relapse is the main cause of death from pediatric acute precursor T-cell leukemia (T-ALL), but the mechanisms underlying relapse… 
Review
2014
Review
2014
Friend or foe: can activating mutations in NOTCH1 contribute to a favorable treatment outcome in patients with T-ALL?
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive malignancy of thymocytes. Despite significant improvement in the… 
Review
2011
Review
2011
TAL2 (T-cell acute lymphoblastic leukemia 2)
Review on TAL2 (T-cell acute lymphoblastic leukemia 2), with data on DNA, on the protein encoded, and where the gene is… 
2010
2010
Gene expression patterns in the histopathological classification of epithelial ovarian cancer.
The purpose of this study was to screen cancer-related genes and to identify histopathological gene expression patterns as… 
Highly Cited
2002
Highly Cited
2002
V(D)J-mediated Translocations in Lymphoid Neoplasms
Most lymphoid malignancies are initiated by specific chromosomal translocations between immunoglobulin (Ig)/T cell receptor (TCR… 
Highly Cited
2001
Highly Cited
2001
J-mediated Translocations in Lymphoid Neoplasms : A Functional Assessment of Genomic Instability by Cryptic Sites
Most lymphoid malignancies are initiated by specific chromosomal translocations between immunoglobulin (Ig)/T cell receptor (TCR… 
1998
1998
Cdkn 2 a , the cyclin-dependent kinase inhibitor encoding p 16 INK 4 a and p 19 ARF , is a candidate for the plasmacytoma susceptibility locus , Pctr 1
Plasma cell tumor induction in mice by pristane is under multigenic control. BALByc mice are susceptible to tumor development… 
Highly Cited
1996
Highly Cited
1996
Association of a novel GTP binding protein, DRG, with TAL oncogenic proteins.
TAL1 is a basic helix-loop-helix (bHLH) protein involved in hematopoietic development. In T cell acute lymphoblastic leukemic… 
1994
1994
Products of the TAL2 oncogene in leukemic T cells: bHLH phosphoproteins with DNA-binding activity.
The TAL2 gene is activated as a result of the (7;9) (q34;q32) translocation, a chromosome defect found in the malignant cells of… 
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