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TAK-701

National Institutes of Health

Papers overview

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2014
2014
Initial testing (Stage 1) of TAK‐701, a humanized hepatocyte growth factor binding antibody, by the pediatric preclinical testing program
TAK‐701 is a humanized antibody that binds hepatocyte growth factor (HGF), thus suppressing c‐Met transduced signaling and c‐Met… 
2011
2011
Abstract 1731: TAK-701, a humanized monoclonal antibody to HGF, reverses gefitinib resistance induced by tumor-derived HGF in non-small cell lung cancer with anEGFRmutation
Most non-small cell lung cancer (NSCLC) tumors with an activating mutation of the epidermal growth factor receptor (EGFR) are… 
2009
2009
Abstract #1244: Monotherapeutic and combination antitumor activities of TAK-701, a humanized anti-hepatocyte growth factor neutralizing antibody, against multiple types of cancer
Signaling of the hepatocyte growth factor (HGF)/c-Met pathway is strongly implicated in cancer progression and represents an… 
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