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TAK-559

National Institutes of Health

Papers overview

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2005
2005
A potent activator of PPARalpha and gamma reduces the vascular cell recruitment and inhibits the intimal thickning in hypercholesterolemic rabbits.
Peroxisome proliferator-activated receptors (PPARs) regulate the vascular cell functions as well as systemic lipid and glucose… 
2004
2004
Studies on non-thiazolidinedione antidiabetic agents. 3. Preparation and biological activity of the metabolites of TAK-559.
Preparation and biological activity of the metabolites of the potent antihyperglycemic and antihyperlipidemic agent, (E)-4-(4-[(5… 
2004
2004
PE-315 Vascular Effects of TAK-559, a New Potent Dual Activator of PPAR α and γ, In Hypercholesterolemic Rabbits(Atherosclerosis, Basic 4 (IHD) : PE54)(Poster Session (English))
2003
2003
Studies on non-thiazolidinedione antidiabetic agents. 2. Novel oxyiminoalkanoic acid derivatives as potent glucose and lipid lowering agents.
We previously reported that (Z)-2-(4-[(5-methyl-2-phenyl-1, 3-oxazol-4-yl)methoxy]benzyloxyimino)-2-(4-phenoxyphenyl)acetic acid… 
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