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TAK-491

Known as: TAK 491, TAK491 
 
National Institutes of Health

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azilsartan medoxomil

Papers overview

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2015
2015
Development, validation and application of the liquid chromatography tandem mass spectrometry method for simultaneous quantification of azilsartan medoxomil (TAK-491), azilsartan (TAK-536), and its 2…
Azilsartan medoxomil potassium salt (TAK-491) is an orally administered angiotensin II type 1 receptor blocker for the treatment… Expand
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2013
2013
Absorption of TAK-491, a new angiotensin II receptor antagonist, in animals.
The absorption process in animals of TAK-491, designed as ester-based prodrug with medoxomil moiety, was evaluated. In the plasma… Expand
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2011
2011
The angiotensin receptor blocker, azilsartan medoxomil (TAK-491), suppresses vascular wall expression of plasminogen activator inhibitor type-I protein potentially facilitating the stabilization of…
Increased expression of plasminogen activator inhibitor type-I (PAI-1) in vessel walls seems to accelerate atherosclerosis… Expand
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Review
2011
Review
2011
Azilsartan Medoxomil: A New Angiotensin II Receptor Antagonist for Treatment of Hypertension
Objective: To evaluate the efficacy, safety, and clinical role of azilsartan medoxomil, an angiotensin II receptor blocker (ARB… Expand
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Review
2011
Review
2011
Azilsartan medoxomil: a new Angiotensin receptor blocker.
BACKGROUND Azilsartan medoxomil is an angiotensin receptor blocker, approved on February 25, 2011 by the US Food and Drug… Expand
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2011
2011
INHIBITION OF THE ANGIOTENSIN II TYPE-1 (AT-1) RECEPTOR BY THE ANGIOTENSIN RECEPTOR BLOCKER AZILSARTAN MEDOXOMIL (TAK-491) SUPPRESSES AORTIC EXPRESSION OF PLASMINOGEN ACTIVATOR INHIBITOR TYPE-I (PAI…
 
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2010
2010
Additive Effect of TAK-491, a New Angiotensin Receptor Blocker, and Pioglitazone, in Reducing Myocardial Infarct Size
PurposeWe assessed the effects of TAK-491 (a newly designed potent and selective ARB) alone and in combination with pioglitazone… Expand
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