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TAK 427

Known as: TAK-427, TAK427 
National Institutes of Health

Papers overview

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2008
2008
Marked impact of P‐glycoprotein on the absorption of TAK‐427 in rats
The role of P‐glycoprotein (P‐gp, ABCB1) on the absorption process was investigated by drug–drug interaction studies of TAK‐427… 
2003
2003
Characteristics of the antihistamine effect of TAK-427, a novel imidazopyridazine derivative
Abstract:Objective and Design: The characteristics of the antihistamine effect of the new antiallergic compound TAK-427 were… 
2003
2003
Synthesis of eosinophil infiltration inhibitors with antihistaminic activity.
A series of [1, 2, 4]triazolo[1, 5-b]pyridazines (5) and imidazo[1, 2-b]pyridazines (6) having cyclic amines was synthesized and… 
2003
2003
Effects of TAK-427 on acute nasal symptoms and nasal obstruction in guinea pig model of experimental allergic rhinitis.
2002
2002
Inhibition of Allergic Dermal Inflammation by the Novel Imidazopyridazine Derivative TAK-427 in a Guinea Pig Experimental Model of Eczema
Antigen challenge by patch ovalbumin emulsion induced an eczema-like skin lesion in epicutaneously sensitized guinea pigs… 
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