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TAK 147

Known as: TAK-147 
National Institutes of Health

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1 relation

Broader (1)

Benzazepines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
Effect of oral administration of zanapezil (TAK‐147) for 21 days on acetylcholine and monoamines levels in the ventral hippocampus of freely moving rats
1 Zanapezil (TAK‐147 (3‐[1benzylpiperdin‐4‐yl]‐1‐(2,3,4,5‐tetrahydro‐1 H‐1‐benzazepin‐8‐yl) propan‐1‐one fumarate)) is a… 
2002
2002
Reversal of scopolamine-induced spatial memory deficits in rats by TAK-147.
AIM To evaluate effect of TAK-147 on spatial memory deficit induced by scopolamine. METHODS Morris water maze was used to… 
2002
2002
Effect of 3-[1-(phenylmethyl)-4-piperidinyl]-1-(2,3,4,5-tetrahydro-1H-1-benzazepin-8-yl)-1-propanone fumarate, a novel acetylcholinesterase inhibitor, on spatial cognitive impairment induced by…
2001
2001
Central and peripheral activity of cholinesterase inhibitors as revealed by yawning and fasciculation in rats.
Highly Cited
2000
Highly Cited
2000
Inhibitory effect of orally administered donepezil hydrochloride (E2020), a novel treatment for Alzheimer's disease, on cholinesterase activity in rats.
Highly Cited
2000
Highly Cited
2000
Comparison of inhibitory activities of donepezil and other cholinesterase inhibitors on acetylcholinesterase and butyrylcholinesterase in vitro.
This study was designed to compare the in vitro inhibitory effects on acetylcholinesterase (AChE) and butyrylcholinesterase… 
Review
2000
Review
2000
Central selective acetylcholinesterase inhibitor with neurotrophic activity: structure-activity relationships of TAK-147 and related compounds.
A series of benzylamino inhibitors of acetylcholinesterase (AChE) have been designed based on a working hypothesis of the enzyme… 
Highly Cited
1999
Highly Cited
1999
TAK-147, an acetylcholinesterase inhibitor, increases choline acetyltransferase activity in cultured rat septal cholinergic neurons
1997
1997
Neurochemical effects of 3-[1-(phenylmethyl)-4-piperidinyl]-1-(2,3,4,5-tetrahydro-1H-1-b enzazepin-8-yl)-1-propanone fumarate (TAK-147), a novel acetylcholinesterase inhibitor, in rats.
We examined the neurochemical effects of 3-[1-(phenylmethyl)-4-piperidinyl]-1-(2,3,4,5-tetrahydro-1H-1-benzaze pin-8-yl)-1… 
1996
1996
Effects of 3-[1-(phenylmethyl)-4-piperidinyl]-1-(2,3,4,5-tetrahydro-1 -H-1-benzazepin-8-yl)-1-propanone fumarate (TAK-147), a novel acetylcholinesterase inhibitor, on impaired learning and memory in…
We examined the effects of p.o. administered 3-[1-(phenylmethyl)-4-piperidinyl]-1-(2,3,4,5-tetrahydro-1H-1-b enzazepin-8- yl)-1… 
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