FAQ

T cell extravasation

Known as: T lymphocyte extravasation, T-cell extravasation, T-lymphocyte extravasation 
The migration of a T cell from the blood vessels into the surrounding tissue. [CL:0000084, GOC:BHF, GOC:mah]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2017
024619922017

Papers overview

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Highly Cited
2010
Highly Cited
2010
Intratumoral T cell infiltration, MHC class I and STAT1 as biomarkers of good prognosis in colorectal cancer.
OBJECTIVE To evaluate immunosurveillance/editing in colorectal cancer. DESIGN Transformation stimulates the production of… (More)
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Highly Cited
2009
Highly Cited
2009
Endothelial basement membrane laminin α5 selectively inhibits T lymphocyte extravasation into the brain
Specific inhibition of the entry of encephalitogenic T lymphocytes into the central nervous system in multiple sclerosis would… (More)
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2009
2009
Beta1 integrins differentially control extravasation of inflammatory cell subsets into the CNS during autoimmunity.
Inhibiting the alpha(4) subunit of the integrin heterodimers alpha(4)beta(1) and alpha(4)beta(7) with the monoclonal antibody… (More)
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Highly Cited
2007
Highly Cited
2007
Wnt signaling induces matrix metalloproteinase expression and regulates T cell transmigration.
Wnts are a family of secreted glycoproteins with diverse developmental roles, including regulation of cell migration; however… (More)
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Highly Cited
2004
Highly Cited
2004
Bimolecular complex between rolling and firm adhesion receptors required for cell arrest; CD44 association with VLA-4 in T cell extravasation.
CD44 on activated T cells can initiate contact and mediate rolling on hyaluronan on endothelial cells. We have shown that the… (More)
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Highly Cited
2003
Highly Cited
2003
T-cell interaction with ICAM-1/ICAM-2 double-deficient brain endothelium in vitro: the cytoplasmic tail of endothelial ICAM-1 is necessary for transendothelial migration of T cells.
Endothelial intercellular adhesion molecule 1 (ICAM-1) and ICAM-2 are both involved in lymphocyte extravasation during… (More)
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2000
2000
The CD44-initiated pathway of T-cell extravasation uses VLA-4 but not LFA-1 for firm adhesion.
Leukocytes extravasate from the blood in response to physiologic or pathologic demands by means of complementary ligand… (More)
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Highly Cited
1997
Highly Cited
1997
Requirement for CD44 in activated T cell extravasation into an inflammatory site.
Leukocytes extravasate from the blood into inflammatory sites through complementary ligand interactions between leukocytes and… (More)
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Highly Cited
1994
Highly Cited
1994
The induction of 72-kD gelatinase in T cells upon adhesion to endothelial cells is VCAM-1 dependent
T cell extravasation from the bloodstream into the perivascular tissue during inflammation involves transmigration through the… (More)
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Highly Cited
1992
Highly Cited
1992
Effects of tumor necrosis factor, lipopolysaccharide, and IL-4 on the expression of vascular cell adhesion molecule-1 in vivo. Correlation with CD3+ T cell infiltration.
We have injected human TNF, LPS, and IL-4 into the skin of baboons to examine regulation of endothelial leukocyte adhesion… (More)
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