FAQ

T cell antigen processing and presentation

Known as: T lymphocyte antigen processing and presentation, T-cell antigen processing and presentation, T-lymphocyte antigen processing and presentation 
The process in which a T cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. [GOC:add, PMID… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2017
01219922017

Papers overview

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Review
2017
Review
2017
The interplay between HLA-B27 and ERAP1/ERAP2 aminopeptidases: from anti-viral protection to spondyloarthritis.
The human leukocyte antigen class I gene HLA-B27 is the strongest risk factor for ankylosing spondylitis (AS), a chronic… (More)
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2015
2015
A proposal to use iterative, small clinical trials to optimize therapeutic HIV vaccine immunogens to launch therapeutic HIV vaccine development.
The HIV cure agenda has rekindled interest in the development of a therapeutic HIV vaccine. An iterative clinical trial strategy… (More)
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Review
2014
Review
2014
Influence of HIV and HCV on T cell antigen presentation and challenges in the development of vaccines
Some of the central challenges for developing effective vaccines against HIV and hepatitis C virus (HCV) are similar. Both… (More)
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Review
2013
Review
2013
Re-Directing CD4+ T Cell Responses with the Flanking Residues of MHC Class II-Bound Peptides: The Core is Not Enough
Recombinant αβ T cell receptors, expressed on T cell membranes, recognize short peptides presented at the cell surface in complex… (More)
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Review
2013
Review
2013
Mycobacterium tuberculosis and the host macrophage: maintaining homeostasis or battling for survival?
Mycobacterium tuberculosis is endowed with the ability to persist within its intracellular niche for years, often tilting the… (More)
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2008
2008
Trafficking of chlamydial antigens to the endoplasmic reticulum of infected epithelial cells.
Confinement of the obligate intracellular bacterium Chlamydia trachomatis to a membrane-bound vacuole, termed an inclusion… (More)
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Review
2001
Review
2001
Immune recognition, response, and regulation: how T lymphocytes do it.
Effective immunity to infectious agents requires the initial recognition of antigen by specific receptors, which leads to the… (More)
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1996
1996
Anergy-associated T cell antigen presentation. A mechanism of infectious tolerance in experimental autoimmune encephalomyelitis.
CD4+ T cells promote immune responses against foreign Ags while actively suppressing responses against self Ags. To address how… (More)
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1992
1992
Differential effects of hemorrhage on Kupffer cells: decreased antigen presentation despite increased inflammatory cytokine (IL-1, IL-6 and TNF) release.
Although studies indicate that simple hemorrhage induces profound depression of cell-mediated immunity and enhances the host's… (More)
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