FAQ

T-Box Brain Protein 1

Known as: T-Brain-1, TBR-1, TES-56 
T-box brain protein 1 (682 aa, ~74 kDa) is encoded by the human TBR1 gene. This protein is involved in both transcriptional regulation and brain… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2000-2017
01220002017

Related topics

Related topics

9 relations
BrainCell NucleusDNA-Binding ProteinsGenes, Regulator
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
T-Box Brain Protein 1
Cell Nucleus
Brain
Transcriptional Regulation
dna binding
Genes, Regulator

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
Brain-specific transcriptional regulator T-brain-1 controls brain wiring and neuronal activity in autism spectrum disorders
T-brain-1 (TBR1) is a brain-specific T-box transcription factor. In 1995, Tbr1 was first identified from a subtractive… (More)
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2015
2015
T-Brain-1--A Potential Master Regulator in Autism Spectrum Disorders.
T-Brain-1 (TBR1), a causative gene in autism spectrum disorders (ASDs), encodes a brain-specific T-box transcription factor. It… (More)
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2014
2014
Neuronal excitation upregulates Tbr1, a high-confidence risk gene of autism, mediating Grin2b expression in the adult brain
The activity-regulated gene expression of transcription factors is required for neural plasticity and function in response to… (More)
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2011
2011
Targeted deletion of CASK-interacting nucleosome assembly protein causes higher locomotor and exploratory activities.
CASK-interacting nucleosome assembly protein (CINAP) has been shown to interact with the calcium/calmodulin-dependent serine… (More)
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2009
2009
Fgfr1 is required for cortical regeneration and repair after perinatal hypoxia.
Chronic postnatal hypoxia causes an apparent loss of cortical neurons that is reversed during recovery (Fagel et al., 2006). The… (More)
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2007
2007
Cytoplasmic distribution of T-box transcription factor Tbr-1 in adult rodent brain.
T-brain-1 (Tbr-1), a brain-specific T-box transcription factor, plays a critical role in cerebral cortex and olfactory bulb… (More)
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2005
2005
A unique subpopulation of Tbr1-expressing deep layer neurons in the developing cerebral cortex.
Cells of the subplate (SP) and deep cortical plate (CP) are among the pioneer neurons of the developing cerebral cortex, an… (More)
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2002
2002
Evolution of developmental functions by the Eomesodermin, T-brain-1, Tbx21 subfamily of T-box genes: insights from amphioxus.
We have identified an amphioxus T-box gene that is orthologous to the Eomesodermin, T-brain-1, and Tbx21 genes of vertebrates… (More)
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2001
2001
Overlapping expression of zebrafish T-brain-1 and eomesodermin during forebrain development
T-box transcription factors are important determinants of embryonic cell fate and behaviour. Two T-box genes are expressed in the… (More)
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2000
2000
A starfish homolog of mouse T-brain-1 is expressed in the archenteron of Asterina pectinifera embryos: possible involvement of two T-box genes in starfish gastrulation.
A cDNA clone for a starfish T-box gene (Ap-Tbr) was isolated and characterized. Molecular phylogenetic analysis showed that the… (More)
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