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T-Box Brain Protein 1

Known as: T-Brain-1, TBR-1, TES-56 
T-box brain protein 1 (682 aa, ~74 kDa) is encoded by the human TBR1 gene. This protein is involved in both transcriptional regulation and brain… Expand
National Institutes of Health

Related topics

Related topics

9 relations
BrainCell NucleusDNA-Binding ProteinsGenes, Regulator
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Calcium/calmodulin-dependent serine protein kinase (CASK), a protein implicated in mental retardation and autism-spectrum disorders, interacts with T-Brain-1 (TBR1) to control extinction of…
Background Human genetic studies have indicated that mutations in calcium/calmodulin-dependent serine protein kinase (CASK… Expand
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Review
2015
Review
2015
Brain-specific transcriptional regulator T-brain-1 controls brain wiring and neuronal activity in autism spectrum disorders
T-brain-1 (TBR1) is a brain-specific T-box transcription factor. In 1995, Tbr1 was first identified from a subtractive… Expand
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2015
2015
T‐Brain‐1 – A Potential Master Regulator in Autism Spectrum Disorders
T‐Brain‐1 (TBR1), a causative gene in autism spectrum disorders (ASDs), encodes a brain‐specific T‐box transcription factor. It… Expand
2014
2014
Neuronal excitation upregulates Tbr1, a high-confidence risk gene of autism, mediating Grin2b expression in the adult brain
The activity-regulated gene expression of transcription factors is required for neural plasticity and function in response to… Expand
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2010
2010
CASK phosphorylation by PKA regulates the protein–protein interactions of CASK and expression of the NMDAR2b gene
J. Neurochem. (2010) 112, 1562–1573. 
2005
2005
A unique subpopulation of Tbr1-expressing deep layer neurons in the developing cerebral cortex
Cells of the subplate (SP) and deep cortical plate (CP) are among the pioneer neurons of the developing cerebral cortex, an… Expand
2005
2005
A unique subpopulation of Tbr1-expressing deep layer neurons in the developing cerebral cortex
Cells of the subplate (SP) and deep cortical plate (CP) are among the pioneer neurons of the developing cerebral cortex, an… Expand
Review
2002
Review
2002
Control of chaotic magnetic fields in tokamaks
Chaotic magnetic field lines play an important role in plasma confinement by tokamaks. They can either be generated in the plasma… Expand
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Highly Cited
2001
Highly Cited
2001
Overlapping expression of zebrafish T-brain-1 and eomesodermin during forebrain development
T-box transcription factors are important determinants of embryonic cell fate and behaviour. Two T-box genes are expressed in the… Expand
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Highly Cited
1995
Highly Cited
1995
T-Brain-1: A homolog of Brachyury whose expression defines molecularly distinct domains within the cerebral cortex
The mechanisms that regulate regional specification and evolution of the cerebral cortex are obscure. To this end, we have… Expand
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