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T 2588

Known as: T-2588 
National Institutes of Health

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cefteram pivoxil

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1987
1987
In vitro activity of ceftriaxone, cefetamet (Ro 15-8074), ceftetrame (Ro 19-5247; T-2588), and fleroxacin (Ro 23-6240; AM-833) versus Neisseria gonorrhoeae and Haemophilus ducreyi
We examined 300 strains of Neisseria gonorrhoeae and 100 strains of Haemophilus ducreyi to determine their in vitro… 
1986
1986
[General pharmacology of T-2588, a new oral cephem antibiotic].
A new oral cephem antibiotic, T-2588, the pivaloyloxymethyl ester of (+)-(6R, 7R)-7-[(Z)-2-(2-amino-4-thiazolyl)-2… 
1986
1986
[Ototoxicity tests for T-2588 in rats].
Ototoxic effects of T-2588 on the spiral and the vestibular organs of the inner ear were investigated in 50 rats of Sprague… 
1986
1986
[Evaluation of T-2588 in the treatment of respiratory tract infection].
T-2588 was used on 55 patients with respiratory tract infections and 44 cases were evaluated; 23 patients with pneumonia, 12… 
1986
1986
[Clinical studies on T-2588 in the field of otorhinolaryngology].
From clinical studies on T-2588, an oral ester type cephem, the following results were obtained. Ten patients with acute… 
1986
1986
[The autoradiographic studies on the distribution of 14C-labeled pivaloyloxymethyl (+)-(6R,7R)- 7-[(Z)-2-(2-amino-4-thiazolyl)-2-methoxyiminoacetamido]- 3-[(5-methyl-2H-tetrazol-2-yl)methyl]-8-o xo-5…
The distribution of T-2588 was studied with whole body autoradiography in normal male mice and pregnant mice using two… 
1986
1986
INFLUENCE OF FOOD ON THE ABSORPTION OF T-2588 IN HUMANS
1986
1986
[Pharmacokinetic studies of a new oral cephem T-2588. Pharmacokinetics in gastrectomized volunteers and the renal excretory system in healthy volunteers].
According to the result of the pharmacokinetic examination of T-2588 (esterified prodrug of T-2525) administered to adult male… 
1986
1986
[Comparative clinical study of T-2588 and bacampicillin in bacterial pneumonia by a double-blind method].
1986
1986
[Effect of single or consecutive administration of T-2588 on hepatic-injured male rats].
The present study was carried out to examine the effect of single or consecutive administration of T-2588 on liver of male rat… 
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