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Systemic Lupus Erythematosus Disease Activity Index

Known as: SLEDAI 
A clinical index for the measurement of disease activity in systemic lupus erythematosus. The index utilizes 24 weighted variables that measure… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2018
05010015019902018

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Research or Clinical Assessment Tool

Related mentions per year

Related mentions per year

1990-2018
1990200020102020
Systemic Lupus Erythematosus Disease Activity Index
Research or Clinical Assessment Tool

Papers overview

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Highly Cited
2011
Highly Cited
2011
Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised, placebo-controlled, phase 3 trial.
BACKGROUND Systemic lupus erythematosus is a heterogeneous autoimmune disease that is associated with B-cell hyperactivity… (More)
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Highly Cited
2011
Highly Cited
2011
A phase III, randomized, placebo-controlled study of belimumab, a monoclonal antibody that inhibits B lymphocyte stimulator, in patients with systemic lupus erythematosus.
OBJECTIVE To assess the efficacy/safety of the B lymphocyte stimulator inhibitor belimumab plus standard therapy compared with… (More)
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Highly Cited
2008
Highly Cited
2008
Association of plasma B lymphocyte stimulator levels and disease activity in systemic lupus erythematosus.
OBJECTIVE To determine the association of plasma B lymphocyte stimulator (BLyS) levels, immunosuppressive therapy, and other… (More)
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Highly Cited
2006
Highly Cited
2006
Association of increased interferon-inducible gene expression with disease activity and lupus nephritis in patients with systemic lupus erythematosus.
OBJECTIVE To study 5 type I interferon (IFN)-inducible genes (LY6E, OAS1, OASL, MX1, and ISG15) in patients with systemic lupus… (More)
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Highly Cited
2003
Highly Cited
2003
Interferon and Granulopoiesis Signatures in Systemic Lupus Erythematosus Blood
Systemic lupus erythematosus (SLE) is a prototype systemic autoimmune disease characterized by flares of high morbidity. Using… (More)
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Highly Cited
2002
Highly Cited
2002
Systemic lupus erythematosus disease activity index 2000.
OBJECTIVE To describe the Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K), a modification of SLEDAI to… (More)
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Highly Cited
2000
Highly Cited
2000
Cytokine production, serum levels and disease activity in systemic lupus erythematosus.
OBJECTIVE T cell abnormalities, B cell hyperactivity and abnormal cytokine production have been implicated to be of pathogenic… (More)
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Highly Cited
1995
Highly Cited
1995
Serum interleukin 10 titers in systemic lupus erythematosus reflect disease activity.
We investigated whether serum titers of interleukin 10 (IL-10), a cytokine known to shift lymphocyte responses towards humoral… (More)
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Highly Cited
1992
Highly Cited
1992
Derivation of the SLEDAI. A disease activity index for lupus patients. The Committee on Prognosis Studies in SLE.
OBJECTIVE To standardize outcome measures in systemic lupus erythematosus (SLE). Three indices were identified which could… (More)
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Highly Cited
1992
Highly Cited
1992
Measurement of disease activity in systemic lupus erythematosus. Prospective validation of 3 clinical indices.
Several clinical indices have been proposed to measure disease activity in patients with systemic lupus erythematosus. Only a few… (More)
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