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Systemic Lupus Erythematosus Disease Activity Index

Known as: SLEDAI 
A clinical index for the measurement of disease activity in systemic lupus erythematosus. The index utilizes 24 weighted variables that measure… 
National Institutes of Health

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Highly Cited
2011
Highly Cited
2011
Development and Initial Validation of the Systemic Lupus Erythematosus Disease Activity Index 2000 Responder Index 50
Objective. To describe the development and validation of the Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K… 
Highly Cited
2010
Highly Cited
2010
Dysregulated balance of Th17 and Th1 cells in systemic lupus erythematosus
IntroductionInterleukin (IL)-17 is a proinflammatory cytokine that is produced largely by a unique CD4+ T-helper (Th) subset… 
Highly Cited
2008
Highly Cited
2008
Difference in disease features between childhood-onset and adult-onset systemic lupus erythematosus.
OBJECTIVE To investigate potential differences between childhood-onset and adult-onset systemic lupus erythematosus (SLE… 
Highly Cited
2005
Highly Cited
2005
Adjusted mean Systemic Lupus Erythematosus Disease Activity Index-2K is a predictor of outcome in SLE.
OBJECTIVE To test the predictability of the adjusted mean Systemic Lupus Erythematosus Disease Activity Index-2K (AMS) for main… 
Highly Cited
2004
Highly Cited
2004
Neuropsychiatric events in systemic lupus erythematosus: attribution and clinical significance.
OBJECTIVE To describe the range and attribution of neuropsychiatric (NP) disease in an unselected cohort of patients with… 
Highly Cited
2004
Highly Cited
2004
Predictors of neuropsychiatric damage in systemic lupus erythematosus: data from the Maryland lupus cohort.
OBJECTIVE To identify factors predictive of significant neuropsychiatric (NP) damage in systemic lupus erythematosus (SLE… 
Highly Cited
2004
Highly Cited
2004
Effects of prasterone on disease activity and symptoms in women with active systemic lupus erythematosus.
OBJECTIVE To determine whether prasterone administration results in improvement or stabilization of systemic lupus erythematosus… 
Highly Cited
2000
Highly Cited
2000
Elevation of proinflammatory cytokine (IL-18, IL-17, IL-12) and Th2 cytokine (IL-4) concentrations in patients with systemic lupus erythematosus
Previous studies have indicated that the autoimmune phenomenon might be caused by an imbalance of T helper cell (Th) cytokines… 
Highly Cited
2000
Highly Cited
2000
Activation of type I interferon system in systemic lupus erythematosus correlates with disease activity but not with antiretroviral antibodies
The objective was to investigate the relation between serum levels of interferon-α (IFN-α), the activity of an endogenous IFN-a… 
Highly Cited
1999
Highly Cited
1999
Patterns of disease activity in systemic lupus erythematosus.
OBJECTIVE To describe patterns of systemic lupus (SLE) disease activity over time. METHODS Disease activity was measured in a… 
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