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Synthetic hTERT DNA Vaccine INO-1400

Known as: INO-1400 
A DNA vaccine consisting of a plasmid encoding the full-length sequence of the tumor-associated antigen (TAA) human telomerase reverse transcriptase… 
National Institutes of Health

Papers overview

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2015
2015
Immunotherapy of tumors with human telomerase reverse transcriptase immortalized human umbilical vein endothelial cells.
Human umbilical endothelial cells (HUVECs) have been proven to be effective in tumor anti-angiogenesis but the mechanism remained… 
2015
2015
The restricted ability of HUVECs to proliferate in vitro also limits their application on a large scale. In the present study, we immortalized HUVECs with hTERT genes by lentiviral infection and…
Human umbilical endothelial cells (HUVECs) have been proven to be effective in tumor anti-angiogenesis but the mechanism remained… 
2011
2011
hTERT expression extends the life-span and maintains the cardiomyogenic potential of mesenchymal stem cells in human umbilical cord blood
Human umbilical cord blood-derived mesenchymal stem cells (UCBMSCs) represent a population of stem cells that are capable of… 
2006
2006
[Functional changes of dendritic cells after infection by recombinant retrovirus carrying human telomerase reverse transcriptase gene fragment].
OBJECTIVE To observe the functional changes of dendritic cells (DCs) after infection by recombinant retrovirus carrying human… 
2003
2003
hTERT experssion in polymorphous low-grade adenocarcinoma of minor salivary gland
Objective:To investigate the expression of human telomerase reverse transcriptase gene (hTERT) in polymorphous low-gracde… 
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