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Syndactyly, type 2

Known as: Synpolydactyly, SYNPOLYDACTYLY 1, Synpolydactyly-1 
A rare genetic disorder characterized by malformations in the hands and feet. The abnormalities include increased number of fingers and toes and… Expand
National Institutes of Health

Papers overview

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Review
2005
Review
2005
The HOM‐C clustered prototype homeobox genes of Drosophila, and their counterparts, the HOX genes in humans, are highly conserved… Expand
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Highly Cited
2004
Highly Cited
2004
Poly-alanine (Ala) tract expansions in transcription factors have been shown to be associated with human birth defects such as… Expand
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Highly Cited
2003
Highly Cited
2003
HOXD13, the most 5' gene of the HOXD cluster, encodes a homeodomain transcription factor with important functions in limb… Expand
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Highly Cited
1998
Highly Cited
1998
Human synpolydactyly (SPD) is an inherited congenital limb malformation caused by mutations in the HOXD13 gene. Heterozygotes are… Expand
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Highly Cited
1998
Highly Cited
1998
Synpolydactyly (SPD) is a dominantly inherited congenital limb malformation consisting of 3/4 syndactyly in the hands and 4/5… Expand
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Highly Cited
1997
Highly Cited
1997
Synpolydactyly (SPD) is a dominantly inherited congenital limb malformation. Typical cases have 3/4 finger and 4/5 toe syndactyly… Expand
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Highly Cited
1996
Highly Cited
1996
Hox genes regulate patterning during limb development. It is believed that they function in the determination of the timing and… Expand
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Highly Cited
1996
Highly Cited
1996
Synpolydactyly (SPD) is a limb malformation that shows a characteristic manifestation in both hands and feet. This condition is… Expand
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Highly Cited
1996
Highly Cited
1996
THE morphogenesis of mammalian digits requires the function of several genes of the HoxD complex during development of limb buds1… Expand
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