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Sulfatases catalyze the hydrolysis of sulfate ester bonds from a wide variety of substrates. Several human inherited diseases are… Expand Sulfatases, which cleave sulfate esters in biological systems, play a key role in regulating the sulfation states that determine… Expand In multiple sulfatase deficiency (MSD), a human inherited disorder, the activities of all sulfatases are impaired due to a defect… Expand The developmental signaling functions of cell surface heparan sulfate proteoglycans (HSPGs) are dependent on their sulfation… Expand In the present study, the concentrations of estrone (E(1)), estradiol (E(2)) and their sulfates (E(1)S and E(2)S), as well as the… Expand BACKGROUND
. Sulfatases catalyze the hydrolysis of sulfuric acid esters from a wide variety of substrates including… Expand This report concerns the evaluation of various estrogens, estrone (El), estradiol (E2), and estrone sulfate (E1S), as well as E1S… Expand Multiple sulfatase deficiency (MSD) is a lysosomal storage disorder characterized by a decreased activity of all known sulfatases… Expand Estrone and estradiol concentrations in breast tumor tissue are an order of magnitude higher than circulating plasma levels in… Expand Abstract 1. An enzyme, "chondroitinase-ABC," has been purified to apparent homogeneity from extracts of Proteus vulgaris, NCTC… Expand