Substitution matrix

In bioinformatics and evolutionary biology, a substitution matrix describes the rate at which one character in a sequence changes to other character… (More)
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Papers overview

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2017
2017
Detecting homologous protein sequences and computing multiple sequence alignments (MSA) are fundamental tasks in molecular… (More)
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2009
2009
While substitution matrices can readily be computed from reference alignments, it is challenging to compute optimal or… (More)
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Highly Cited
2007
Highly Cited
2007
AAindex is a database of numerical indices representing various physicochemical and biochemical properties of amino acids and… (More)
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2006
2006
Detecting remote homologies by direct comparison of protein sequences remains a challenging task. We had previously developed a… (More)
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Highly Cited
2005
Highly Cited
2005
Codon substitution probabilities are used in many types of molecular evolution studies such as determining Ka/Ks ratios, creating… (More)
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2005
2005
By using a mixture model for the density distribution of the three pseudobond angles formed by Cα atoms of four consecutive… (More)
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2004
2004
Different approaches to using substitution matrices in kernel functions for protein secondary structure prediction (PSSP) with… (More)
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Highly Cited
2003
Highly Cited
2003
Substitution matrices have been useful for sequence alignment and protein sequence comparisons. The BLOSUM series of matrices… (More)
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Highly Cited
1999
Highly Cited
1999
Intake of metabolisable energy (ME) when forages and grains are fed together to ruminants may, due to digestive and metabolic… (More)
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1991
1991
Regulatory mechanisms of hepatic apolipoprotein synthesis were studied in groups of male Sprague-Dawley rats made severely… (More)
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