Structure of optic stalk

Known as: Optic Stalk 
A paired narrow neural tube extension connecting the optic vesicles with the forebrain during early neural development of the embryo, and which is… (More)
National Institutes of Health

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Coloboma of optic discEmbryonic eye

Papers overview

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2007
2007
Focal adhesion kinase controls morphogenesis of the Drosophila optic stalk.
Photoreceptor cell axons (R axons) innervate optic ganglia in the Drosophila brain through the tubular optic stalk. This… (More)
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Highly Cited
2005
Highly Cited
2005
Expression of the homeobox gene Pitx2 in neural crest is required for optic stalk and ocular anterior segment development.
Heterozygous mutations in the homeobox gene, PITX2, result in ocular anterior segment defects and a high incidence of early-onset… (More)
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Highly Cited
2005
Highly Cited
2005
The hedgehog-PKA pathway regulates two distinct steps of the differentiation of retinal ganglion cells: the cell-cycle exit of retinoblasts and their neuronal maturation.
In the developing zebrafish retina, neurogenesis is initiated in cells adjacent to the optic stalk and progresses to the entire… (More)
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Highly Cited
2003
Highly Cited
2003
Hedgehog signalling maintains the optic stalk-retinal interface through the regulation of Vax gene activity.
During early formation of the eye, the optic vesicle becomes partitioned into a proximal domain that forms the optic nerve and a… (More)
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Highly Cited
2003
Highly Cited
2003
Retinal ganglion cell-derived sonic hedgehog signaling is required for optic disc and stalk neuroepithelial cell development.
The development of optic stalk neuroepithelial cells depends on Hedgehog (Hh) signaling, yet the source(s) of Hh protein in the… (More)
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Highly Cited
2001
Highly Cited
2001
Coordinate expression of Fgf8, Otx2, Bmp4, and Shh in the rostral prosencephalon during development of the telencephalic and optic vesicles.
Previous studies suggest that Fgf8 has a key role in regulating vertebrate development. In the rostral head of the embryonic… (More)
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Highly Cited
1999
Highly Cited
1999
Early retinal development in the zebrafish, Danio rerio: light and electron microscopic analyses.
The morphological differentiation of the zebrafish retina was analyzed by using light (LM) and transmission electron (TEM… (More)
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Highly Cited
1998
Highly Cited
1998
Characterization of three novel members of the zebrafish Pax2/5/8 family: dependency of Pax5 and Pax8 expression on the Pax2.1 (noi) function.
The mammalian Pax2, Pax5 and Pax8 genes code for highly related transcription factors, which play important roles in embryonic… (More)
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Highly Cited
1995
Highly Cited
1995
The first retinal axons and their microenvironment in zebrafish: cryptic pioneers and the pretract.
The initial development of the optic tract was studied with light and electron microscopy in the zebrafish (Danio rerio… (More)
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Highly Cited
1987
Highly Cited
1987
Evidence for migration of oligodendrocyte–type-2 astrocyte progenitor cells into the developing rat optic nerve
Formation of myelinated tracts in central nervous system (CNS) regions such as the optic nerve seems to depend on two glial cell… (More)
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