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Structure of genital tubercle

Known as: Genital tubercle 
 
National Institutes of Health

Papers overview

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2016
2016
Computational modeling and simulation of genital tubercle development.
Hypospadias is a developmental defect of urethral tube closure that has a complex etiology involving genetic and environmental… Expand
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2015
2015
Tissue-specific roles of FGF signaling in external genitalia development.
BACKGROUND The developmental processes of the genital tubercle (GT), the anlage of the external genitalia, possess several… Expand
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2014
2014
Coordinated activity of Spry1 and Spry2 is required for normal development of the external genitalia.
Development of the mammalian external genitalia is controlled by a network of signaling molecules and transcription factors… Expand
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Highly Cited
2009
Highly Cited
2009
Temporal and spatial dissection of Shh signaling in genital tubercle development
Genital tubercle (GT) initiation and outgrowth involve coordinated morphogenesis of surface ectoderm, cloacal mesoderm and… Expand
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Highly Cited
2009
Highly Cited
2009
Dosage-dependent hedgehog signals integrated with Wnt/β-catenin signaling regulate external genitalia formation as an appendicular program
Embryonic appendicular structures, such as the limb buds and the developing external genitalia, are suitable models with which to… Expand
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2007
2007
HOXA13 directly regulates EphA6 and EphA7 expression in the genital tubercle vascular endothelia.
Hypospadias, a common defect affecting the growth and closure of the external genitalia, is often accompanied by gross… Expand
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2006
2006
Gene expression profiles in mouse urethral development.
OBJECTIVE To analyse the gene expression profiles of the mouse genital tubercle (GT) during urethral tube development at… Expand
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2004
2004
Anatomical studies of the fibroblast growth factor-10 mutant, Sonic Hedge Hog mutant and androgen receptor mutant mouse genital tubercle.
OBJECTIVES Congenital genital abnormalities have a diverse spectrum from hypospadias to cloacal anomalies. The molecular events… Expand
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Highly Cited
2001
Highly Cited
2001
Unique functions of Sonic hedgehog signaling during external genitalia development.
Coordinated growth and differentiation of external genitalia generates a proximodistally elongated structure suitable for… Expand
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Highly Cited
2000
Highly Cited
2000
Molecular analysis of external genitalia formation: the role of fibroblast growth factor (Fgf) genes during genital tubercle formation.
The molecular mechanisms underlying the development of the external genitalia in mammals have been very little examined. Recent… Expand
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