Structure of alpha Cell of islet

Known as: Cells, Glucagon-Secreting, Alpha cell of pancreatic islet, Alpha cell 
A type of pancreatic cell representing about 5-20% of the islet cells. Alpha cells secrete GLUCAGON.
National Institutes of Health

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Highly Cited
2015
Highly Cited
2015
Type 2 diabetes (T2D) is characterized by chronic hyperglycemia resulting from a deficiency in insulin signaling, because of… (More)
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Highly Cited
2011
Highly Cited
2011
Exercise, obesity and type 2 diabetes are associated with elevated plasma concentrations of interleukin-6 (IL-6). Glucagon-like… (More)
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Highly Cited
2011
Highly Cited
2011
Type 2 diabetes is a bi-hormonal disease characterised by relative hypoinsulinaemia and hyperglucagonaemia with elevated blood… (More)
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Highly Cited
2009
Highly Cited
2009
Glucagon plays an important role in glucose homeostasis by regulating hepatic glucose output in both normo- and hypoglycemic… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Exogenous use of the intestinal hormone glucagon-like peptide 1 (GLP-1) lowers glycaemia by stimulation of insulin… (More)
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Review
2005
Review
2005
Although there is abundant evidence that hyperglucagonaemia plays a key role in the development of hyperglycaemia in type 2… (More)
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Highly Cited
2003
Highly Cited
2003
Glucagon, the counter-regulatory hormone to insulin, is secreted from pancreatic alpha cells in response to low blood glucose. To… (More)
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Highly Cited
1984
Highly Cited
1984
To determine if glucagon secretion is under physiological control of intra-islet insulin, pancreata from normal rats were… (More)
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Highly Cited
1973
Highly Cited
1973
Despite excessive glucagon responses to infusion of arginine, plasma glucagon did not rise in six juvenile-type diabetics during… (More)
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Highly Cited
1970
Highly Cited
1970
The development of a glucagon radioimmunoassay with a relatively high degree of specificity for pancreatic glucagon made possible… (More)
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