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Stromal Neoplasm
Known as:
stromal tumours
, Stromal Cell Tumor
, tumors stromal
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A benign or malignant mesenchymal neoplasm composed of stromal cells. Representative examples include gastrointestinal stromal tumor, endometrial…
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National Institutes of Health
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Related topics
Related topics
9 relations
Connective Tissue Cells
Connective and Soft Tissue
Neoplastic Cell
Neoplastic Stromal Cell
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Narrower (1)
Stromal sarcoma
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Lung cancers with acquired resistance to EGFR inhibitors occasionally harbor BRAF gene mutations but lack mutations in KRAS, NRAS, or MEK1
K. Ohashi
,
L. Sequist
,
+21 authors
W. Pao
Proceedings of the National Academy of Sciences…
2012
Corpus ID: 36976640
Acquired resistance to EGF receptor (EGFR) tyrosine kinase inhibitors (TKIs) is inevitable in metastatic EGFR-mutant lung cancers…
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Review
2010
Review
2010
Relationship between exposure to sunitinib and efficacy and tolerability endpoints in patients with cancer: results of a pharmacokinetic/pharmacodynamic meta-analysis
B. Houk
,
C. Bello
,
B. Poland
,
L. Rosen
,
G. Demetri
,
R. Motzer
Cancer Chemotherapy and Pharmacology
2010
Corpus ID: 16787808
PurposeIn this pharmacokinetic/pharmacodynamic meta-analysis, we investigated relationships between clinical endpoints and…
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Highly Cited
2008
Highly Cited
2008
Dose‐dependent, complete response to imatinib of a metastatic mucosal melanoma with a K642E KIT mutation
J. Lutzky
,
J. Bauer
,
B. Bastian
Pigment Cell & Melanoma Research
2008
Corpus ID: 27531249
Dear Sir, We recently reported mutations and copy number increases of KIT in 40% or mucosal and acral melanomas, as well as 30…
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Review
2007
Review
2007
Management of ovarian stromal cell tumors.
N. Colombo
,
G. Parma
,
V. Zanagnolo
,
Alessandra Insinga
Journal of Clinical Oncology
2007
Corpus ID: 42741605
PURPOSE To describe the clinical management of ovarian stromal cell tumors, which are a heterogeneous group of neoplasms that…
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Highly Cited
2007
Highly Cited
2007
Hypothyroidism in patients with metastatic renal cell carcinoma treated with sunitinib.
B. Rini
,
I. Tamaskar
,
+6 authors
R. Bukowski
Journal of the National Cancer Institute
2007
Corpus ID: 2425454
Sunitinib is an inhibitor of the vascular endothelial growth factor and platelet-derived growth factor receptors, and it has…
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Highly Cited
2005
Highly Cited
2005
Imatinib as a novel antifibrotic agent in bleomycin-induced pulmonary fibrosis in mice.
Y. Aono
,
Y. Nishioka
,
+5 authors
S. Sone
American Journal of Respiratory and Critical Care…
2005
Corpus ID: 12259419
Imatinib mesylate is a potent and specific tyrosine kinase inhibitor against c-ABL, BCR-ABL, and c-KIT, and has been demonstrated…
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Review
2004
Review
2004
Hedgehog signaling promotes prostate xenograft tumor growth.
Lian-Ming Fan
,
Carmen V. Pepicelli
,
+10 authors
W. Bushman
Endocrinology
2004
Corpus ID: 19036364
During fetal prostate development, Sonic hedgehog (Shh) expression by the urogenital sinus epithelium activates Gli-1 expression…
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Highly Cited
2004
Highly Cited
2004
Kinase Inhibition with BAY 43–9006 in Renal Cell Carcinoma
T. Ahmad
,
T. Eisen
Clinical Cancer Research
2004
Corpus ID: 6941557
BAY 43–9006 is an oral inhibitor of CRAF, wild-type BRAF, mutant V599E BRAF, vascular endothelial growth factor receptor (VEGFR…
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Highly Cited
2003
Highly Cited
2003
Classification and subtype prediction of adult soft tissue sarcoma by functional genomics.
N. Segal
,
P. Pavlidis
,
+8 authors
C. Cordon-Cardo
American Journal of Pathology
2003
Corpus ID: 15727499
Highly Cited
2003
Highly Cited
2003
Structure of a c-Kit Product Complex Reveals the Basis for Kinase Transactivation*
C. Mol
,
K. B. Lim
,
+7 authors
D. McRee
Journal of Biological Chemistry
2003
Corpus ID: 25677210
The c-Kit proto-oncogene is a receptor protein-tyrosine kinase associated with several highly malignant human cancers. Upon…
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