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The ability to transform biologically exogenous daunomycinone, 13-dihydrodaunomycinone, aklavinone, 7-deoxyaklavinone… (More)
The wild strainStreptomyces coeruleorubidus JA 10092 was found to segregate into two spontaneous morphological variants (spo-1… (More)
Mutants ofStreptomyces coeruleorubidus, blocked in the biosynthesis of anthracycline antibiotics of the daunomycine complex, were… (More)
7-Deoxy-13-dihydrodaunomycinone was isolated from three strains ofStreptomyces coeruleorubidus. Its production was found to rise… (More)
A total of 351 auxotrophic mutants with different antibiotic activity, including several mutants with activity higher than that… (More)