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Sterol Regulatory Element Binding Proteins

Known as: SREBP Proteins, Sterol Regulatory Element Binding Proteins [Chemical/Ingredient] 
Sterol regulatory element binding proteins are basic helix-loop-helix leucine zipper transcription factors that bind the sterol regulatory element… Expand
National Institutes of Health

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In BloodProcess of secretionagonistsantagonists & inhibitors
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Papers overview

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2011
2011
Ethanol-induced alterations in fatty acid-related lipids in serum and tissues in mice.
BACKGROUND Chronic alcohol consumption is a major factor for several human diseases, and alcoholism is associated with a host of… Expand
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2010
2010
Short communication: Identification of the bovine sterol regulatory element binding protein-1c promoter and its activation by liver X receptor.
Sterol regulatory element binding proteins (SREBP) are a family of transcription factors that regulate cholesterogenesis and… Expand
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2010
2010
n-3 and n-6 Polyunsaturated fatty acids suppress sterol regulatory element binding protein activity and increase flow of non-esterified cholesterol in HepG2 cells.
The plasma lipid-lowering effect of PUFA, one of their main beneficial effects, is considered to be related to the regulation of… Expand
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2006
2006
Androgen regulation of lipogenic pathways in the mouse meibomian gland.
We hypothesize that androgens regulate lipogenesis in the meibomian gland. To test this hypothesis, we sought to determine… Expand
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Highly Cited
2005
Highly Cited
2005
Calorie restriction modulates renal expression of sterol regulatory element binding proteins, lipid accumulation, and age-related renal disease.
Sterol regulatory element binding proteins (SREBP) are major regulators of fatty acid and cholesterol synthesis. This study found… Expand
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Highly Cited
2005
Highly Cited
2005
In support of fatty acid synthase (FAS) as a metabolic oncogene: extracellular acidosis acts in an epigenetic fashion activating FAS gene expression in cancer cells.
Relatively little information exists on the ultimate molecular mechanisms by which the lipogenic enzyme Fatty Acid Synthase (FAS… Expand
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Highly Cited
2004
Highly Cited
2004
Soy isoflavones affect sterol regulatory element binding proteins (SREBPs) and SREBP-regulated genes in HepG2 cells.
Soy intake reduces cholesterol levels. However, both the identity of the soy component or components that contribute to this… Expand
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2004
2004
Vascular endothelial growth factor activation of sterol regulatory element binding protein: a potential role in angiogenesis.
By stimulating the migration and proliferation of endothelial cells (ECs), vascular endothelial growth factor (VEGF) is a potent… Expand
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2004
2004
Regulation of group VIA phospholipase A2 expression by sterol availability.
Several lines of evidence suggest that glycerophospholipid mass is maintained through the coordinate regulation of CTP… Expand
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Highly Cited
2000
Highly Cited
2000
Sterol regulatory element binding proteins (SREBP)-1a and SREBP-2 are linked to the MAP-kinase cascade.
The classic sterol regulatory cis element (sre-1) in the LDL receptor promoter mediates sterol regulatory element binding protein… Expand
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