FAQ

Sterol Regulatory Element Binding Proteins

Known as: SREBP Proteins, Sterol Regulatory Element Binding Proteins [Chemical/Ingredient] 
Sterol regulatory element binding proteins are basic helix-loop-helix leucine zipper transcription factors that bind the sterol regulatory element… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2005-2017
012320052017

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Related topics

10 relations
In BloodProcess of secretionadministration & dosageagonists
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Sterol Regulatory Element Binding Proteins
physiological aspects
agonists
chemical synthesis
standards characteristics
Process of secretion

Papers overview

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Review
2017
Review
2017
Regulation of Sterol Biosynthesis in the Human Fungal Pathogen Aspergillus fumigatus: Opportunities for Therapeutic Development
Sterols are a major component of eukaryotic cell membranes. For human fungal infections caused by the filamentous fungus… (More)
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2015
2015
Activation of hepatic CREBH and Insig signaling in the anti-hypertriglyceridemic mechanism of R-α-lipoic acid.
The activation of sterol regulatory element binding proteins (SREBPs) is regulated by insulin-induced genes 1 and 2 (Insig-1 and… (More)
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2014
2014
Zinc Finger Transcription Factors Displaced SREBP Proteins as the Major Sterol Regulators during Saccharomycotina Evolution
In most eukaryotes, including the majority of fungi, expression of sterol biosynthesis genes is regulated by Sterol-Regulatory… (More)
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2013
2013
Dutasteride and Metformin Reduce the Growth of LNCaP Cells and Alter the SREBP-1 Pathway
Prostate cancer (PCa) is the second most prevalent cancer in men after lung cancer. Prostate cancer development and progression… (More)
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Review
2013
Review
2013
Function of site-2 proteases in bacteria and bacterial pathogens.
Site-2 proteases (S2Ps) are a class of intramembrane metalloproteases named after the founding member of this protein family… (More)
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2012
2012
Sterols regulate 3β-hydroxysterol Δ24-reductase (DHCR24) via dual sterol regulatory elements: cooperative induction of key enzymes in lipid synthesis by Sterol Regulatory Element Binding Proteins.
3β-Hydroxysterol Δ24-reductase (DHCR24) catalyzes a final step in cholesterol synthesis, and has been ascribed diverse functions… (More)
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2012
2012
Central Role of SREBP-2 in the Pathogenesis of Osteoarthritis
BACKGROUND Recent studies have implied that osteoarthritis (OA) is a metabolic disease linked to deregulation of genes involved… (More)
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Highly Cited
2011
Highly Cited
2011
Statins Promote the Regression of Atherosclerosis via Activation of the CCR7-Dependent Emigration Pathway in Macrophages
HMG-CoA reductase inhibitors (statins) decrease atherosclerosis by lowering low-density-lipoprotein cholesterol. Statins are also… (More)
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2009
2009
Fibrillar collagen inhibits cholesterol biosynthesis in human aortic smooth muscle cells.
OBJECTIVE Integrin-mediated cell adhesion to type I fibrillar collagen regulates gene and protein expression, whereas little is… (More)
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2008
2008
Gossypin up-regulates LDL receptor through activation of ERK pathway: a signaling mechanism for the hypocholesterolemic effect.
Hypercholesterolemia is one of the major risk factors for the development of cardiovascular disease. This study aims to elucidate… (More)
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