Stereocilia

Known as: Stereocilium, Stereovilli, Stereovillus 
An actin-based protrusion from the apical surface of auditory and vestibular hair cells and of neuromast cells. These protrusions are supported by a… (More)
National Institutes of Health

Related topics

Related topics

17 relations
Apical Domain of the EpitheliumAuditory Hair CellCadherin-23Cochlear outer hair cell
(More)

Broader (2)

Ciliastereocilium bundle

Narrower (1)

stereocilium membrane

Papers overview

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Highly Cited
2005
Highly Cited
2005
Myosin-XVa is required for tip localization of whirlin and differential elongation of hair-cell stereocilia
Stereocilia are microvilli-derived mechanosensory organelles that are arranged in rows of graded heights on the apical surface of… (More)
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Highly Cited
2004
Highly Cited
2004
Cadherin 23 is a component of the tip link in hair-cell stereocilia
Mechanoelectrical transduction, the conversion of mechanical force into electrochemical signals, underlies a range of sensory… (More)
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Highly Cited
2004
Highly Cited
2004
An actin molecular treadmill and myosins maintain stereocilia functional architecture and self-renewal
We have previously shown that the seemingly static paracrystalline actin core of hair cell stereocilia undergoes continuous… (More)
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Highly Cited
2003
Highly Cited
2003
Myosin XVa localizes to the tips of inner ear sensory cell stereocilia and is essential for staircase formation of the hair bundle.
Mutations of the gene encoding unconventional myosin XVa are associated with sensorineural deafness in humans (DFNB3) and shaker… (More)
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Highly Cited
2001
Highly Cited
2001
Mutations in Cdh23, encoding a new type of cadherin, cause stereocilia disorganization in waltzer, the mouse model for Usher syndrome type 1D
Mouse chromosome 10 harbors several loci associated with hearing loss, including waltzer (v), modifier-of deaf waddler (mdfw) and… (More)
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Highly Cited
2000
Highly Cited
2000
The Deaf Jerker Mouse Has a Mutation in the Gene Encoding the Espin Actin-Bundling Proteins of Hair Cell Stereocilia and Lacks Espins
The espins are actin-bundling proteins of brush border microvilli and Sertoli cell-spermatid junctions. We have determined that… (More)
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Highly Cited
1998
Highly Cited
1998
Plasma membrane Ca2+-ATPase extrudes Ca2+ from hair cell stereocilia.
Mechanically sensitive hair cells of the auditory and vestibular systems use Ca2+ to control adaptation of mechanical… (More)
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Highly Cited
1995
Highly Cited
1995
Calcium imaging of single stereocilia in hair cells: Localization of transduction channels at both ends of tip links
Mechanically gated "transduction" channels in inner ear hair cells are thought to be connected to tip links stretched between… (More)
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Highly Cited
1986
Highly Cited
1986
Actin filaments, stereocilia, and hair cells of the bird cochlea. III. The development and differentiation of hair cells and stereocilia.
The cochleae of chick embryos of 8 days of incubation until hatching (21 days) were examined by scanning electron microscopy… (More)
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Highly Cited
1984
Highly Cited
1984
Single-neuron labeling and chronic cochlear pathology. III. Stereocilia damage and alterations of threshold tuning curves
Tuning curves were obtained from 100 to 150 auditory-nerve fibers spanning the range of characteristic frequencies (CFs) in each… (More)
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