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Staphylocoagulase

An extracellular protein which specifically forms a complex with human prothrombin. This complex named staphylothrombin can clot fibrinogen without… 
National Institutes of Health

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Broader (1)

Coagulase

Papers overview

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Highly Cited
2009
Highly Cited
2009
Genetic Diversity of Staphylocoagulase Genes (coa): Insight into the Evolution of Variable Chromosomal Virulence Factors in Staphylococcus aureus
Background The production of staphylocoagulase (SC) causing the plasma coagulation is one of the important characteristics of… 
Highly Cited
2006
Highly Cited
2006
Fibrinogen Substrate Recognition by Staphylocoagulase·(Pro)thrombin Complexes*
Thrombin generation and fibrinogen (Fbg) clotting are the ultimate proteolytic reactions in the blood coagulation pathway… 
Highly Cited
2004
Highly Cited
2004
The staphylocoagulase family of zymogen activator and adhesion proteins
Abstract.Staphylocoagulase (SC) secreted by Staphylococcus aureus is a potent non-proteolytic activator of the blood coagulation… 
Highly Cited
2003
Highly Cited
2003
Staphylocoagulase is a prototype for the mechanism of cofactor-induced zymogen activation
Many bacterial pathogens secrete proteins that activate host trypsinogen-like enzyme precursors, most notably the proenzymes of… 
Highly Cited
1992
Highly Cited
1992
Molecular typing of Staphylococcus aureus on the basis of coagulase gene polymorphisms
Staphylocoagulase, a major phenotypic determinant of Staphylococcus aureus, exists in multiple allelic forms, in part because of… 
Highly Cited
1987
Highly Cited
1987
Nucleotide sequence of the staphylocoagulase gene: its unique COOH-terminal 8 tandem repeats.
The entire staphylocoagulase gene of Staphylococcus aureus strain BB was cloned on a MboI restriction endonuclease fragment… 
Highly Cited
1986
Highly Cited
1986
A New Method to Assay Des-γ-carboxyprothrombin
Highly Cited
1985
Highly Cited
1985
Enzymatic properties of staphylothrombin, an active molecular complex formed between staphylocoagulase and human prothrombin.
Staphylocoagulase with a molecular weight of 64,000 and subspecies ranging in molecular weight from 36,000 to 64,000 were… 
1978
1978
The determination of prothrombin using synthetic chromogenic substrates; choice of a suitable activator.
1974
1974
Prothrombin Brussels, a new congenital defective protein.
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