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Staphylocoagulase

An extracellular protein which specifically forms a complex with human prothrombin. This complex named staphylothrombin can clot fibrinogen without… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Background The production of staphylocoagulase (SC) causing the plasma coagulation is one of the important characteristics of… Expand
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Highly Cited
2006
Highly Cited
2006
Thrombin generation and fibrinogen (Fbg) clotting are the ultimate proteolytic reactions in the blood coagulation pathway… Expand
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2004
2004
Abstract.Staphylocoagulase (SC) secreted by Staphylococcus aureus is a potent non-proteolytic activator of the blood coagulation… Expand
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Highly Cited
2003
Highly Cited
2003
Many bacterial pathogens secrete proteins that activate host trypsinogen-like enzyme precursors, most notably the proenzymes of… Expand
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Highly Cited
1992
Highly Cited
1992
Staphylocoagulase, a major phenotypic determinant of Staphylococcus aureus, exists in multiple allelic forms, in part because of… Expand
Highly Cited
1987
Highly Cited
1987
The entire staphylocoagulase gene of Staphylococcus aureus strain BB was cloned on a MboI restriction endonuclease fragment… Expand
Highly Cited
1985
Highly Cited
1985
Staphylocoagulase with a molecular weight of 64,000 and subspecies ranging in molecular weight from 36,000 to 64,000 were… Expand
1985
1985
A staphylocoagulase-binding region in human prothrombin was studied by utilizing several fragments prepared from prothrombin by… Expand
Highly Cited
1983
Highly Cited
1983
The activation of human prothrombin by the bacterial protein staphylocoagulase proceeds via the formation of a very stable… Expand
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Highly Cited
1975
Highly Cited
1975
The reaction between prothrombin and staphylocoagulase was investigated and the following conclusions were drawn: (a) Optimal… Expand
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