Specific Pathogen Free

Known as: Pathogen Free, Specific, Pathogen Frees, Specific 
 
National Institutes of Health

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Specific Pathogen-Free Organisms

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Highly Cited
2011
Highly Cited
2011
Reduced anxiety-like behavior and central neurochemical change in germ-free mice.
BACKGROUND There is increasing interest in the gut-brain axis and the role intestinal microbiota may play in communication… (More)
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Highly Cited
2011
Highly Cited
2011
Normal gut microbiota modulates brain development and behavior.
Microbial colonization of mammals is an evolution-driven process that modulate host physiology, many of which are associated with… (More)
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2008
2008
Specific pathogen free conditions prevent transthyretin amyloidosis in mouse models
Transthyretin (TTR) associated amyloidosis is an autosomal dominant disorder characterized by peripheral and autonomic neuropathy… (More)
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2008
2008
Transmission of pathogenic respiratory bacteria to specific pathogen free pigs at slaughter.
The purpose of this study was to evaluate the transmission of pathogenic respiratory bacteria to thirteen 5-month-old specific… (More)
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2006
2006
Rapid transmission of the protozoan parasite Histomonas meleagridis in turkeys and specific pathogen free chickens following cloacal infection with a mono-eukaryotic culture.
In the present investigation, the pathogenicity and transmission of a mono-eukaryotic culture of Histomonas meleagridis for… (More)
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Review
2005
Review
2005
Disease and health management in Asian aquaculture.
Asia contributes more than 90% to the world's aquaculture production. Like other farming systems, aquaculture is plagued with… (More)
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Highly Cited
2004
Highly Cited
2004
Postnatal microbial colonization programs the hypothalamic-pituitary-adrenal system for stress response in mice.
Indigenous microbiota have several beneficial effects on host physiological functions; however, little is known about whether or… (More)
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Highly Cited
2001
Highly Cited
2001
Loss of transforming growth factor beta signalling in the intestine contributes to tissue injury in inflammatory bowel disease.
BACKGROUND Inflammatory bowel disease (IBD) is a chronic inflammation of the gastrointestinal tract caused by an abnormal and… (More)
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Highly Cited
2000
Highly Cited
2000
Lactobacillus GG prevents recurrence of colitis in HLA-B27 transgenic rats after antibiotic treatment.
BACKGROUND AND AIMS Bacteroides vulgatus induces colitis in gnotobiotic HLA-B27 transgenic (TG) rats while broad spectrum… (More)
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Highly Cited
1998
Highly Cited
1998
Inflammatory bowel disease-like enteritis and caecitis in a senescence accelerated mouse P1/Yit strain.
BACKGROUND A new subline of the senescence accelerated mouse (SAM) P1/Yit strain has been established which shows spontaneous… (More)
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