Sodium-Phosphate Cotransporter Proteins

Known as: Sodium Phosphate Cotransporter, Phosphate Transporter, Sodium, Cotransporter Proteins, Sodium-Phosphate 
A family of symporters that facilitate sodium-dependent membrane transport of phosphate.
National Institutes of Health

Related topics

Related topics

10 relations
In BloodProcess of secretionSLC34A1 geneSLC34A2 gene
(More)

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Autosomal-Recessive Mutations in SLC34A1 Encoding Sodium-Phosphate Cotransporter 2A Cause Idiopathic Infantile Hypercalcemia.
Idiopathic infantile hypercalcemia (IIH) is characterized by severe hypercalcemia with failure to thrive, vomiting, dehydration… (More)
Is this relevant?
Highly Cited
2009
Highly Cited
2009
Therapeutic effects of anti-FGF23 antibodies in hypophosphatemic rickets/osteomalacia.
X-linked hypophosphatemia (XLH), characterized by renal phosphate wasting, is the most common cause of vitamin D-resistant… (More)
Is this relevant?
2008
2008
Estrogen downregulates the proximal tubule type IIa sodium phosphate cotransporter causing phosphate wasting and hypophosphatemia.
Estrogen treatment causes significant hypophosphatemia in patients. To determine the mechanisms responsible for this effect, we… (More)
Is this relevant?
2008
2008
Luminal fructose inhibits rat intestinal sodium-phosphate cotransporter gene expression and phosphate uptake.
BACKGROUND While searching by microarray for sugar-responsive genes, we inadvertently discovered that sodium-phosphate… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Review
2007
Review
2007
The emerging role of the fibroblast growth factor-23-klotho axis in renal regulation of phosphate homeostasis.
Normal mineral ion homeostasis is tightly controlled by numerous endocrine factors that coordinately exert effects on intestine… (More)
  • figure 1
  • table 1
  • table 2
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Vitamin D receptor-independent FGF23 actions in regulating phosphate and vitamin D metabolism.
FGF23 suppresses both serum phosphate and 1,25-dihydroxyvitamin D [1,25D] levels in vivo. Because 1,25D itself is a potent… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Nephrolithiasis and osteoporosis associated with hypophosphatemia caused by mutations in the type 2a sodium-phosphate cotransporter.
BACKGROUND Epidemiologic studies suggest that genetic factors confer a predisposition to the formation of renal calcium stones or… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Targeted disruption of the mouse NHERF-1 gene promotes internalization of proximal tubule sodium-phosphate cotransporter type IIa and renal phosphate wasting.
Na+/H+ exchanger regulatory factor (NHERF)-1 and NHERF-2, two structurally related protein adapters containing tandem PSD-95… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Age-dependent regulation of rat intestinal type IIb sodium-phosphate cotransporter by 1,25-(OH)(2) vitamin D(3).
The current studies were designed to characterize type IIb sodium-inorganic phosphate (P(i)) cotransporter (NaP(i)-IIb… (More)
  • figure 2
  • figure 1
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Characterization of a murine type II sodium-phosphate cotransporter expressed in mammalian small intestine.
An isoform of the mammalian renal type II Na/Pi-cotransporter is described. Homology of this isoform to described mammalian and… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?