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Smad Proteins, Receptor-Regulated

Known as: Smad Proteins, Receptor-Regulated [Chemical/Ingredient], Smad Proteins, Receptor Regulated, R-Smad Proteins 
A family of smad proteins that undergo PHOSPHORYLATION by CELL SURFACE RECEPTORS in response to TRANSFORMING GROWTH FACTOR BETA; ACTIVIN; or BONE… Expand
National Institutes of Health

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8 relations
In BloodProcess of secretionagonistsantagonists & inhibitors
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Ablation of the mammalian lectin galectin‐8 induces bone defects in mice
Mice overexpressing galectin‐8 [gal‐8 transgenic (Tg)], a secreted mammalian lectin, exhibit enhanced bone turnover and reduced… Expand
Review
2013
Review
2013
New insights into extracellular and post-translational regulation of TGF-β family signalling pathways.
Members of the transforming growth factor-β (TGF-β) family of secreted proteins are present in all multicellular animals. TGF… Expand
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2011
2011
Suppression of BMP-Smad signaling axis-induced osteoblastic differentiation by small C-terminal domain phosphatase 1, a Smad phosphatase.
Bone morphogenetic proteins (BMPs) induce osteoblastic differentiation in myogenic cells via the phosphorylation of Smads. Two… Expand
Highly Cited
2008
Highly Cited
2008
Laser Capture Microdissection and Protein Microarray Analysis of Human Non-small Cell Lung Cancer
Little is known about lung carcinoma epidermal growth factor (EGF) kinase pathway signaling within the context of the tissue… Expand
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Highly Cited
2007
Highly Cited
2007
Inhibition of Allergen-Induced Airway Remodeling in Smad 3-Deficient Mice1
Intracellular signaling pathways that converge on Smad 3 are used by both TGF-β and activin A, key cytokines implicated in the… Expand
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2005
2005
辐射诱导Egr-1调控腺病毒介导Smad 7基因对Lewis肺癌生物学行为影响的在体研究
目的研究射线诱导下Egr-1基因启动子调控腺病毒介导的Smad 7基因在C57BL/6J小鼠Lewis肺癌原发病灶内表达后,对原发灶及远处肺转移发生的影响.方法将Egr-1基因启动子的辐射敏感元件和Smad7 cDNA包装到复制缺陷型腺病毒内,制备成AD… Expand
Highly Cited
2003
Highly Cited
2003
Stepwise formation of a SMAD activity gradient during dorsal-ventral patterning of the Drosophila embryo
Genetic evidence suggests that the Drosophila ectoderm is patterned by a spatial gradient of bone morphogenetic protein (BMP… Expand
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Highly Cited
2002
Highly Cited
2002
Smad 3 May Regulate Follicular Growth in the Mouse Ovary1
Abstract Although Smad 3 is known to serve as a signaling intermediate for the transforming growth factor beta (TGFβ) family in… Expand
Highly Cited
2001
Highly Cited
2001
Smad proteins function as co-modulators for MEF2 transcriptional regulatory proteins.
An emerging theme in transforming growth factor-ss (TGF-ss) signalling is the association of the Smad proteins with diverse… Expand
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1998
1998
human Smad familyであるSmad5 geneのfull length cDNA、ゲノム構造プロモーターのクローニングとヒト肺癌における変異解析
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