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Smad Proteins, Receptor-Regulated

Known as: Smad Proteins, Receptor-Regulated [Chemical/Ingredient], Smad Proteins, Receptor Regulated, R-Smad Proteins 
A family of smad proteins that undergo PHOSPHORYLATION by CELL SURFACE RECEPTORS in response to TRANSFORMING GROWTH FACTOR BETA; ACTIVIN; or BONE… Expand
National Institutes of Health

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In BloodProcess of secretionagonistsantagonists & inhibitors
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Papers overview

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2018
2018
Ablation of the mammalian lectin galectin-8 induces bone defects in mice.
Mice overexpressing galectin-8 [gal-8 transgenic (Tg)], a secreted mammalian lectin, exhibit enhanced bone turnover and reduced… Expand
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Review
2013
Review
2013
New insights into extracellular and post-translational regulation of TGF-β family signalling pathways.
Members of the transforming growth factor-β (TGF-β) family of secreted proteins are present in all multicellular animals. TGF… Expand
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2012
2012
Stimulated erythropoiesis with secondary iron loading leads to a decrease in hepcidin despite an increase in bone morphogenetic protein 6 expression.
The BMP/SMAD signalling pathway plays an important role in iron homeostasis, regulating hepcidin expression in response to body… Expand
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2011
2011
Suppression of BMP-Smad signaling axis-induced osteoblastic differentiation by small C-terminal domain phosphatase 1, a Smad phosphatase.
Bone morphogenetic proteins (BMPs) induce osteoblastic differentiation in myogenic cells via the phosphorylation of Smads. Two… Expand
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Highly Cited
2007
Highly Cited
2007
Inhibition of Allergen-Induced Airway Remodeling in Smad 3-Deficient Mice1
Intracellular signaling pathways that converge on Smad 3 are used by both TGF-β and activin A, key cytokines implicated in the… Expand
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2005
2005
辐射诱导Egr-1调控腺病毒介导Smad 7基因对Lewis肺癌生物学行为影响的在体研究
目的研究射线诱导下Egr-1基因启动子调控腺病毒介导的Smad 7基因在C57BL/6J小鼠Lewis肺癌原发病灶内表达后,对原发灶及远处肺转移发生的影响.方法将Egr-1基因启动子的辐射敏感元件和Smad7 cDNA包装到复制缺陷型腺病毒内,制备成AD… Expand
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2003
2003
Stepwise formation of a SMAD activity gradient during dorsal-ventral patterning of the Drosophila embryo
Genetic evidence suggests that the Drosophila ectoderm is patterned by a spatial gradient of bone morphogenetic protein (BMP… Expand
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2002
2002
Smad 3 May Regulate Follicular Growth in the Mouse Ovary1
Abstract Although Smad 3 is known to serve as a signaling intermediate for the transforming growth factor beta (TGFβ) family in… Expand
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2001
2001
Smad proteins function as co-modulators for MEF2 transcriptional regulatory proteins.
An emerging theme in transforming growth factor-ss (TGF-ss) signalling is the association of the Smad proteins with diverse… Expand
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1998
1998
human Smad familyであるSmad5 geneのfull length cDNA、ゲノム構造プロモーターのクローニングとヒト肺癌における変異解析
 
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