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Smad Proteins, Inhibitory
Known as:
I-Smad Proteins
, Inhibitory Smad Proteins
, Smad Proteins, Inhibitory [Chemical/Ingredient]
A sub-family of smad proteins that inhibit cell signaling by RECEPTOR-REGULATED SMAD PROTEINS. They form autoinhibitory feedback loops in the TGF…
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National Institutes of Health
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8 relations
In Blood
Process of secretion
agonists
antagonists & inhibitors
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Cytokine sensitivity screening highlights BMP4 pathway signaling as a therapeutic opportunity in ER+ breast cancer
K. Shee
,
A. Jiang
,
+9 authors
T. Miller
The FASEB Journal
2019
Corpus ID: 52131074
Despite the success of approved systemic therapies for estrogen receptor α (ER)‐positive breast cancer, drug resistance remains…
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2017
2017
Fibulin-6 regulates pro-fibrotic TGF-β responses in neonatal mouse ventricular cardiac fibroblasts
Arpita Chowdhury
,
L. Hasselbach
,
F. Echtermeyer
,
N. Jyotsana
,
G. Theilmeier
,
C. Herzog
Scientific Reports
2017
Corpus ID: 26408928
Fibulin-6, an essential component of extracellular matrix determines the architecture of cellular junctions in tissues undergoing…
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2015
2015
SMAD signaling in the airways of healthy versus asthmatic rhesus macaques highlights a relationship between inflammation and BMPs
Therese M. Lynn
,
Emer L. Molloy
,
+8 authors
S. O'Dea
2015
Corpus ID: 207773544
Bone Morphogenetic Protein (BMP) signaling is important for correct lung morphogenesis and there is evidence of BMP signaling re…
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2013
2013
ALK2 and BMPR2 knockdown and endothelin-1 production by pulmonary microvascular endothelial cells.
Gregory P. Star
,
M. Giovinazzo
,
D. Langleben
Microvascular Research
2013
Corpus ID: 3219547
2010
2010
Bone Morphogenetic Protein (BMP)-7 expression is decreased in human hypertensive nephrosclerosis
C. Bramlage
,
B. Tampe
,
+9 authors
G. Müller
BMC Nephrology
2010
Corpus ID: 9127038
BackgroundBone Morphogenetic Protein (BMP)-7 is protective in different animal models of acute and chronic kidney disease. Its…
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Highly Cited
2005
Highly Cited
2005
Kinetic Analysis of Smad Nucleocytoplasmic Shuttling Reveals a Mechanism for Transforming Growth Factor β-Dependent Nuclear Accumulation of Smads
B. Schmierer
,
C. Hill
Molecular and Cellular Biology
2005
Corpus ID: 7973217
ABSTRACT Upon transforming growth factor β (TGF-β) stimulation, Smads accumulate in the nucleus, where they regulate gene…
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2005
2005
SMAD-Signaltransduktionsmechanismen bei COPD: Verminderung der SMAD6 und -7 mRNA Expression durch Zigarettenrauch
D. Groneberg
,
J. Springer
,
F. Scholz
,
C. Peiser
,
Q. Dinh
,
A. Fischer
2005
Corpus ID: 80522673
2001
2001
Implication des voies de signalisation des protéines JNK et SMAD dans l'apoptose régulée par le TGF-β1
Anne Mazars
2001
Corpus ID: 82499162
Le TGF-beta appartient a une famille de mediateurs locaux impliques dans le controle de la proliferation et de la differenciation…
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1999
1999
BMP2シグナル伝達分子 Smad ファミリーによるCbfa-1の発現調節と骨芽細胞への分化誘導との関連
西村 理行
,
波多 賢二
,
米田 俊之
1999
Corpus ID: 83363664
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