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Sheddase Inhibitor INCB007839
An orally bioavailable inhibitor of the ADAM (A Disintegrin And Metalloprotease) family of multifunctional membrane-bound proteins with potential…
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National Institutes of Health
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Highly Cited
2004
Highly Cited
2004
A Phase I Study of Oral BMS-275291, a Novel Nonhydroxamate Sheddase-Sparing Matrix Metalloproteinase Inhibitor, in Patients with Advanced or Metastatic Cancer
N. Rizvi
,
J. Humphrey
,
+8 authors
H. Hurwitz
Clinical Cancer Research
2004
Corpus ID: 2560263
Purpose: BMS-275291 is a novel broad-spectrum inhibitor of matrix metalloproteinase (MMPs) rationally designed to spare a class…
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