Skip to search formSkip to main contentSkip to account menu

Shc-Grb2-Sos complex

Known as: Shc-Grb2-Sos complex location, Shc-Grb2-mSos1 complex location, EGF stimulated, Shc-Grb2-mSos1 complex, EGF stimulated 
A protein complex that contains Grb2, the adaptor protein Shc and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
Dynamics and control of the ERK signaling pathway: Sensitivity, bistability, and oscillations
Cell signaling is the process by which extracellular information is transmitted into the cell to perform useful biological… 
2018
2018
Intrinsic spin Hall conductivity of the semimetals MoTe2 and WTe2
We report a comprehensive study on the intrinsic spin Hall conductivity (SHC) of semimetals MoTe2 and WTe2 by ab initio… 
2017
2017
Duration of dual antiplatelet therapy in patients treated with percutaneous coronary intervention for coronary chronic total occlusion
Background The duration of dual antiplatelet therapy (DAPT) after drug-eluting stent implantation in coronary chronic total… 
2012
2012
Prediction of Risk Factors for Coronary Heart Disease Using Framingham Risk Score in Korean Men
Background Currently, there is sparse data available on the relationship between coronary heart disease (CHD) and its risk… 
2001
2001
Linkage of Rapid Estrogen Action to MAPK Activation by ER-Shc Association and Shc Pathway Activation
E2 rapidly activates MAPK in breast cancer cells, and the mechanism for this effect has not been fully identified. Since growth… 
Highly Cited
2000
Highly Cited
2000
New Role for Shc in Activation of the Phosphatidylinositol 3-Kinase/Akt Pathway
ABSTRACT Most, if not all, cytokines activate phosphatidylinositol 3-kinase (PI-3K). Although many cytokine receptors have direct… 
Highly Cited
2000
Highly Cited
2000
The Requirement of Both Extracellular Regulated Kinase and p38 Mitogen-activated Protein Kinase for Stimulation of Cytosolic Phospholipase A2 Activity by Either FcγRIIA or FcγRIIIB in Human…
The signal transduction pathways initiated by opsonized zymosan (OZ) leading to activation of cytosolic phospholipase A2 (cPLA2… 
1999
1999
Activation of Raf-1 during experimental gastric ulcer healing is Ras-mediated and protein kinase C-independent.
Highly Cited
1997
Highly Cited
1997
Shc contains two Grb2 binding sites needed for efficient formation of complexes with SOS in B lymphocytes
Cross-linking of the B-cell antigen receptor (BCR) induces tyrosine phosphorylation of Shc, which is believed to lead to the… 
Highly Cited
1996
Highly Cited
1996
A novel pathway from phosphorylation of tyrosine residues 239/240 of Shc, contributing to suppress apoptosis by IL‐3.
Interleukin 3 (IL‐3) not only induces DNA synthesis of haematopoietic cells but also maintains their viability by suppressing… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)