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Severe Malaria

Known as: Complicated Malaria 
Acute malaria with signs of organ dysfunction, severe anemia (hemoglobin less than 5 g/dL or hematocrit less than 15%) and/or hyperparasitemia… 
National Institutes of Health

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Malaria

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Insecticide‐treated nets for preventing malaria
Abstract Background A previous version of this Cochrane Review identified that insecticide‐treated nets (ITNs) are effective at… 
Highly Cited
2016
Highly Cited
2016
Composition of the gut microbiota modulates the severity of malaria
Significance Plasmodium infections cause >200 million cases of malaria and ∼1 million deaths annually. Although these infections… 
Highly Cited
2012
Highly Cited
2012
Oxidative stress in children with severe malaria.
Fifty cases of severe malaria were studied for their oxidant and antioxidant status. Severe anemia (54%) was the most common… 
Review
2011
Review
2011
Oral iron supplements for children in malaria-endemic areas.
BACKGROUND Iron-deficiency anaemia is common during childhood. Iron supplementation has been claimed to increase the risk of… 
Highly Cited
2005
Highly Cited
2005
Increased prevalence of severe malaria in HIV-infected adults in South Africa.
BACKGROUND Conflicting reports exist regarding the impact of human immunodeficiency virus (HIV) infection on the risk of severe… 
Highly Cited
2000
Highly Cited
2000
Hemoglobin C associated with protection from severe malaria in the Dogon of Mali, a West African population with a low prevalence of hemoglobin S.
The malaria hypothesis proposes a survival advantage for individuals with hemoglobin variants in areas of endemic Plasmodium… 
Highly Cited
1999
Highly Cited
1999
The role of red blood cell polymorphisms in resistance and susceptibility to malaria.
In regions highly endemic for Plasmodium falciparum malaria, red cell polymorphisms that confer resistance to severe disease are… 
Highly Cited
1998
Highly Cited
1998
Short report: severe malaria associated with blood group.
The ABO blood groups are not linked to the incidence of simple malaria infection but have been associated with rosette formation… 
Highly Cited
1997
Highly Cited
1997
Prognostic significance of reduced red blood cell deformability in severe falciparum malaria.
Severe falciparum malaria is associated with microvascular obstruction resulting from sequestration of erythrocytes containing… 
Highly Cited
1993
Highly Cited
1993
Plasmodium falciparum: in vitro studies of the pharmacodynamic properties of drugs used for the treatment of severe malaria.
The speed and stage specificity of antimalarial drug action on the metabolic activities of cultured Plasmodium falciparum were… 
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