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Sertoli cell differentiation

The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is… 
National Institutes of Health

Related topics

Related topics

2 relations

Narrower (1)

Sertoli cell development

Broader (1)

male gonad development

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Di(2-Ethylhexyl) Phthalate Exposure In Utero Damages Sertoli Cell Differentiation Via Disturbance of Sex Determination Pathway in Fetal and Postnatal Mice.
Mice may share similar mechanism with human underlying reproductive toxicity induced by di(2-ethylhexyl) phthalate (DEHP), which… 
Highly Cited
2012
Highly Cited
2012
Activin signaling regulates Sertoli cell differentiation and function.
Throughout development, activin A signaling stimulates proliferation and inhibits differentiation of testicular Sertoli cells. A… 
Highly Cited
2007
Highly Cited
2007
Fibroblast growth factor receptor 2 regulates proliferation and Sertoli differentiation during male sex determination
Targeted mutagenesis of Fgf9 in mice causes male-to-female sex reversal. Among the four FGF receptors, FGFR2 showed two highly… 
2004
2004
Comparative Immunohistochemical Analysis of Granulosa and Sertoli Components in Ovarian Sex Cord-Stromal Tumors with Mixed Differentiation: Potential Implications for Derivation of Sertoli…
Summary:Granulosa cell tumors of the ovary occasionally show admixed Sertoli components, just as tumors that are predominantly… 
Highly Cited
2003
Highly Cited
2003
Thyroid hormone, retinoic acid, and testosterone suppress proliferation and induce markers of differentiation in cultured rat sertoli cells.
This study uses a high purity cell culture system to extend previous observations of factors controlling the end of the Sertoli… 
Highly Cited
2003
Highly Cited
2003
Thyroid Hormone , Retinoic Acid , and Testosterone Suppress Proliferation and Induce Markers of Differentiation in Cultured Rat Sertoli Cells
This study uses a high purity cell culture system to extend previous observations of factors controlling the end of the Sertoli… 
1997
1997
Role of basic-helix-loop-helix transcription factors in Sertoli cell differentiation: identification of an E-box response element in the transferrin promoter.
Sertoli cells are critical for testicular function and maintenance of the spermatogenic process. The induction of Sertoli cell… 
1996
1996
Transcriptional regulation of sertoli cell differentiation by follicle-stimulating hormone at the level of the c-fos and transferrin promoters.
One of the primary endocrine hormones that influence the onset of Sertoli cell differentiation at puberty and help maintain… 
1995
1995
Regulation of Sertoli cell aromatase activity by cell density and prolonged stimulation with FSH, EGF, insulin and IGF-I at different moments of pubertal development
Highly Cited
1980
Highly Cited
1980
Sertoli tumors of the ovary. A clinicopathologic study of 28 cases with ultrastructural observations
The clinical and pathologic features of 28 Sertoli tumors of the ovary are presented. Seventeen of the 28 neoplasms had a… 
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