Sertoli cell differentiation

The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1953-2018
051019532017

Papers overview

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2009
2009
Activation by the Y-encoded testis determining factor SRY and maintenance of expression of the Sox9 gene encoding the central… (More)
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Highly Cited
2008
Highly Cited
2008
The mammalian Y chromosome acts as a dominant male determinant as a result of the action of a single gene, Sry, whose role in sex… (More)
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Highly Cited
2005
Highly Cited
2005
We have raised an antibody specifically recognizing endogenous mouse SRY protein and used it to investigate the molecular and… (More)
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Highly Cited
2004
Highly Cited
2004
Sex determination in mammals directs an initially bipotential gonad to differentiate into either a testis or an ovary. This… (More)
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Highly Cited
2002
Highly Cited
2002
During embryogenesis, primordial germ cells (PGCs) have the potential to enter either spermatogenesis or oogenesis. In a female… (More)
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Highly Cited
2000
Highly Cited
2000
The functions of estrogen receptors (ERs) in mouse ovary and genital tracts were investigated by generating null mutants for… (More)
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Highly Cited
1999
Highly Cited
1999
In mammals a single gene on the Y chromosome, Sry, controls testis formation. One of the earliest effects of Sry expression is… (More)
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Highly Cited
1996
Highly Cited
1996
Heterozygous mutations in SOX9 lead to a human dwarfism syndrome, Campomelic dysplasia. Consistent with a role in sex… (More)
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Highly Cited
1995
Highly Cited
1995
In the mouse, Sry is expressed by germ cells in the adult testis and by somatic cells in the genital ridge. Transcripts in the… (More)
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Highly Cited
1985
Highly Cited
1985
Sertoli cell preparations isolated from 10-day-old rats were cultured on three different substrates: plastic, a matrix deposited… (More)
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