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Septin-9

Known as: Ov/Br Septin, Ovarian/Breast Septin, MLL Septin-Like Fusion Protein 
Septin-9 (586 aa, ~65 kDa) is encoded by the human SEPT9 gene. This protein plays a role in the mediation of cytoskeletal filament formation.
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Background Determination of methylated Septin 9 (mSEPT9) in plasma has been shown to be a sensitive and specific biomarker for… Expand
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Highly Cited
2014
Highly Cited
2014
BACKGROUND Epi proColon® is a new blood-based colorectal cancer (CRC) screening test designed to determine the methylation status… Expand
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Highly Cited
2013
Highly Cited
2013
BackgroundThe septin 9 gene (SEPT9) codes for a GTP-binding protein associated with filamentous structures and cytoskeleton… Expand
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2013
2013
Pleural effusions (PE) are a common clinical problem. The discrimination between benign (BPE), malignant (MPE) and paramalignant… Expand
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Highly Cited
2012
Highly Cited
2012
BACKGROUND & AIMS Several noninvasive tests have been developed for colorectal cancer (CRC) screening. We compared the… Expand
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Highly Cited
2012
Highly Cited
2012
Background Methylated Septin 9 (SEPT9) is a sensitive biomarker for colorectal cancer (CRC) from peripheral blood. However, its… Expand
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Highly Cited
2011
Highly Cited
2011
Mammalian SEPT9 is positioned at the end of septin octamers and is necessary for octamer assembly into polymers necessary for… Expand
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Highly Cited
2010
Highly Cited
2010
SEPT9 localizes the vesicle-tethering exocyst complex to the midbody to promote daughter cell separation. 
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Highly Cited
2009
Highly Cited
2009
BACKGROUND The presence of aberrantly methylated SEPT9 DNA in plasma is highly correlated with the occurrence of colorectal… Expand
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Highly Cited
2005
Highly Cited
2005
Hereditary neuralgic amyotrophy (HNA) is an autosomal dominant recurrent neuropathy affecting the brachial plexus. HNA is… Expand
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