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Scopolamine

Known as: 6-beta,7-beta-Epoxy-3-alpha-tropanyl S-(-)-tropate, (1S,3S,5R,6R,7S)-6,7-Epoxytropan-3-yl (2S)-3-hydroxy-2-phenylpropanoate, Benzeneacetic Acid, alpha-(hydroxymethyl)-,(1alpha,2beta,4beta,5alpha,7beta)-9-methyl-3-oxa-9-azatricyclo(3.3.1.02,4)non-7-yl ester,(alphaS)- 
A tropane alkaloid derived from plants of the nightshade family (Solanaceae), specifically Hyoscyamus niger and Atropa belladonna, with… 
National Institutes of Health

Related topics

Related topics

41 relations
72 HR Scopolamine 0.0139 MG/HR Transdermal System [Transderm Scop]AmnesiaAngle Closure GlaucomaBromides

Broader (7)

AlkaloidsAminesAnalgesicsAnticholinergic Agents

Narrower (6)

B-DonnaBoro-ScopolDonnatalScopolamine Derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
DFT‐GIAO1H NMR chemical shifts prediction for the spectral assignment and conformational analysis of the anticholinergic drugs (−)‐scopolamine and (−)‐hyoscyamine
The relatively large chemical shift differences observed in the 1H NMR spectra of the anticholinergic drugs (−)‐scopolamine 1 and… 
1999
1999
Synthesis and characterization of fluorescent ligands for the norepinephrine transporter: potential neuroblastoma imaging agents.
Radiolabeled m-iodobenzylguanidine (MIBG) is a tumor-seeking radioactive drug used in the diagnosis and treatment of… 
1997
1997
Antinociceptive profile of 3-alpha-tropanyl 2-(4-Cl-phenoxy)butyrate (SM-21) [corrected]: a novel analgesic with a presynaptic cholinergic mechanism of action.
The antinociceptive effect of (+/-)-3-alpha-tropanyl 2-(4-Cl-phenoxy)butyrate [corrected] (SM-21) (10-40 mg kg(-1) s.c., 10-30 mg… 
1994
1994
Solid-state stereochemistry of (-)-scopolamine hydrobromide sesquihydrate, a new polymorph of the anticholinergic drug.
The solid-state structure of (-)-scopolamine hydrobromide sesquihydrate was determined by single-crystal X-ray diffraction… 
Highly Cited
1991
Highly Cited
1991
Drugs which stimulate or facilitate central cholinergic transmission interact synergistically with delta-9-tetrahydrocannabinol to produce marked catalepsy in mice
1989
1989
A comparison of the value of hyoscine butylbromide and glucagon on aorto iliac intravenous digital subtraction.
: The diagnostic quality of intravenous subtraction aorto-iliac arteriograms was assessed in 60 patients randomly allocated to… 
1975
1975
Hypothermic effect of cocaine in rats.
Cocaine injected intraperitoneally into rats resulted in a dose-dependent hypothermia. Intracerebral injection of smaller doses… 
1969
1969
A comparison of the effects of (-)-hyoscine and amylobarbitone sodium on measurements of post-rotational turning sensation and nystagmus.
Following the reports of earlier workers an experiment was carried out to assess the possible value of cupulometric techniques… 
1947
1947
Psychological test performance under hyoscine; a case of post-infectious encephalopathy.
1945
1945
Psychological Reactions in the Wounded
way be precipitated in a susceptible patient. It may be that the development of an acute glaucoma, which on rare occasions… 
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