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Schizotrypanum

 
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Evolutionary insights from bat trypanosomes: morphological, developmental and phylogenetic evidence of a new species, Trypanosoma (Schizotrypanum) erneyi sp. nov., in African bats closely related to…
Parasites of the genus Trypanosoma are common in bats and those of the subgenus Schizotrypanum are restricted to bats throughout… Expand
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Highly Cited
2004
Highly Cited
2004
Activity of the New Triazole Derivative Albaconazole against Trypanosoma (Schizotrypanum) cruzi in Dog Hosts
ABSTRACT Albaconazole is an experimental triazole derivative with potent and broad-spectrum antifungal activity and a remarkably… Expand
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Highly Cited
2000
Highly Cited
2000
Activities of the Triazole Derivative SCH 56592 (Posaconazole) against Drug-Resistant Strains of the Protozoan ParasiteTrypanosoma (Schizotrypanum) cruzi in Immunocompetent and Immunosuppressed…
ABSTRACT We have studied the in vivo activity of the new experimental triazole derivative SCH 56592 (posaconazole) against a… Expand
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Highly Cited
2000
Highly Cited
2000
In Vitro Antiproliferative Effects and Mechanism of Action of the New Triazole Derivative UR-9825 against the Protozoan Parasite Trypanosoma (Schizotrypanum)cruzi
ABSTRACT We describe the in vitro antiproliferative effects of the new triazole derivative UR-9825 against the protozoan… Expand
Highly Cited
1998
Highly Cited
1998
Antiproliferative Effects and Mechanism of Action of SCH 56592 against Trypanosoma (Schizotrypanum)cruzi: In Vitro and In Vivo Studies
ABSTRACT We have investigated the antiproliferative effects of SCH 56592, a new experimental triazole, against Trypanosoma… Expand
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Highly Cited
1995
Highly Cited
1995
Modification of the sterol composition of Trypanosoma (Schizotrypanum) cruzi epimastigotes by delta 24(25)-sterol methyl transferase inhibitors and their combinations with ketoconazole.
We report a detailed analysis of the sterol composition of Trypanosoma cruzi epimastigotes grown in the absence or presence of… Expand
Highly Cited
1993
Highly Cited
1993
Mevinolin (lovastatin) potentiates the antiproliferative effects of ketoconazole and terbinafine against Trypanosoma (Schizotrypanum) cruzi: in vitro and in vivo studies.
We have studied the antiproliferative effects of mevinolin (lovastatin), an inhibitor of 3-hydroxy-3-methyl-glutaryl-coenzyme A… Expand
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Highly Cited
1990
Highly Cited
1990
Ultrastructural alterations induced by two ergosterol biosynthesis inhibitors, ketoconazole and terbinafine, on epimastigotes and amastigotes of Trypanosoma (Schizotrypanum) cruzi.
We report the ultrastructural alterations induced during the proliferative stages of Trypanosoma (Schizotrypanum) cruzi, the… Expand
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1990
1990
Inhibition of phosphoenolpyruvate carboxykinase from Trypanosoma (Schizotrypanum) cruzi epimastigotes by 3-mercaptopicolinic acid: in vitro and in vivo studies.
3-mercaptopicolinic acid (3MP) was shown to be a powerful and specific inhibitor of the phosphoenolpyruvate carboxykinase (PEP… Expand
Highly Cited
1988
Highly Cited
1988
Antiproliferative synergism of the allylamine SF 86-327 and ketoconazole on epimastigotes and amastigotes of Trypanosoma (Schizotrypanum) cruzi.
We have investigated the growth-inhibitory effects of two ergosterol biosynthesis inhibitors, the dioxolane imidazole… Expand
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